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Pitt Scientists Create ‘Living Eye Drop’ to Speed Cornea Healing
University of Pittsburgh scientists have turned a harmless eye-dwelling bacterium into a “living eye drop” that speeds corneal healing in mice. The early-stage work hints at future one-time treatments that could protect and repair the eye from within.
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New Tool Exposes Hidden Activity in HIV Reservoir Cells
A new tool called HIV-seq is giving scientists their clearest view yet of HIV-infected cells that linger despite treatment. The findings could guide future strategies to calm or clear these long-lived reservoir cells.
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ASU Study Reveals How Water Can Make Nanomedicine Safer, Smarter
Arizona State University scientists have directly measured how water clings to drug-carrying nanoparticles, uncovering a key principle that could make future nanomedicines safer and more precise. Their work lays a thermodynamic foundation for designing nanoparticles that behave predictably inside the body.
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Super-Sensitive HIT Cell Therapy Wipes Out Solid Tumors in Mice
Columbia researchers have created a next-generation cell therapy, called HIT cells, that can detect and destroy solid tumors in mice by homing in on a hard-to-spot cancer marker. The work could open a new front in the fight against some of the deadliest cancers.
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UCLA Scientists Give Cancer-Fighting T Cells a Tumor-Proof Fuel
UCLA scientists have found a way to feed cancer-fighting immune cells with a fuel that tumors cannot steal. The strategy could help next-generation CAR-T and other T cell therapies work better against tough solid tumors.
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Engineered ‘Hungry’ Bacteria Show Promise for Attacking Tumors
A University of Waterloo team is reprogramming bacteria to invade and consume solid tumors from the inside out. Their synthetic biology approach could one day turn a common soil microbe into a highly targeted cancer treatment.
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New Polymer ‘Trash Collectors’ Target Cancer’s Toughest Proteins
Northwestern University researchers have designed polymer “trash collectors” that grab cancer’s most stubborn proteins and drag them to the cell’s waste bin. The approach halted tumor growth in mice and could open the door to new treatments for cancers long considered undruggable.
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Brain Neurons, Not Just Muscles, Found to Drive Endurance Gains
A new study from The Jackson Laboratory and the University of Pennsylvania finds that key neurons in the brain must activate after a workout for endurance to improve. The discovery could one day help people who cannot exercise intensely still gain some of its protective benefits.
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How Bacteria May Help Drive Breast Cancer
Johns Hopkins scientists have traced how certain gut and breast bacteria can push breast cancer to grow and spread by hijacking a single enzyme. Their findings spotlight a new drug target that could help protect patients whose microbiomes are out of balance.
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Chronic Inflammation Traps Immune Repair Cells, Study Finds
Chronic inflammation can quietly sabotage the body’s own repair crew. A new UNC-Chapel Hill study shows how key immune cells get stuck in harmful states and points to ways scientists might one day reset them.