Davos Alzheimer’s Collaborative Takes Global Stand to Improve Dementia Diagnosis

The Davos Alzheimer’s Collaborative launches the Accurate Diagnosis project to improve the global timely diagnosis of Alzheimer’s and related dementias, deploying cutting-edge blood biomarkers across healthcare systems in five countries.

In a groundbreaking move towards better Alzheimer’s care, the Davos Alzheimer’s Collaborative (DAC) has launched a global initiative to deploy blood biomarkers (BBMs) to enhance the timely and accurate diagnosis of Alzheimer’s disease and related dementias (ADRD). This ambitious project, known as the Accurate Diagnosis project, will be implemented in healthcare systems across Germany, Japan, the Netherlands, the UK and the United States.

The Accurate Diagnosis project, spearheaded by the DAC Healthcare System Preparedness (DAC-SP) team, is set to revolutionize the field of Alzheimer’s diagnostics. Traditional diagnostic pathways often suffer from delays and inconsistencies, and the introduction of BBMs aims to address these issues by providing a more streamlined, effective approach.

“The DAC Healthcare System Preparedness team is eager to build and share learnings during the next phase of implementing these critical triaging tools,” Tim MacLeod, DAC Healthcare System Preparedness Director, said in a statement. “This project expands the learnings from our previous program on early detection of cognitive impairment to ensure an increasing number of Alzheimer’s disease patients receive the right care, at the right time.”

Participating healthcare systems will deploy and evaluate the use of BBMs and confirmatory Alzheimer’s pathology testing, enabling providers to integrate these tests into everyday clinical practice. This marks a significant shift from the current reliance on research settings to a broader clinical application, promising quicker and more accurate diagnoses for patients worldwide.

Commenting on the initiative, Founding Chairman George Vradenburg stated, “We are committed to advancing timely diagnosis of Alzheimer’s disease in all resource settings, in every country, thus leveraging learnings for the benefit of all. The Accurate Diagnosis project will help catalyze healthcare system change and will make patient-centered care and support more widely accessible.”

Site leaders from the involved countries forming a Community of Practice are expected to share experiences and collaboratively tackle common challenges over the 18-month project. Their findings and resources will be integrated into the DAC-SP Early Detection Blueprint, aiding other healthcare systems aiming to adopt similar methodologies.

Selected for their robust scientific and clinical capabilities, as well as their commitment to diverse patient demographics, the initial sites include prominent institutions, such as the University of Kansas Alzheimer’s Disease Research Center, Imperial College London and Tokyo Metropolitan Institute for Geriatrics and Gerontology. These institutions will implement the cutting-edge diagnostic tools while receiving BBM and CSF test kits from key partners like C2N Diagnostics, Quanterix, Fujirebio and Roche.

The Davos Alzheimer’s Collaborative, launched at the World Economic Forum in 2021, was inspired by successful global health campaigns against diseases such as HIV/AIDS and COVID-19. By introducing cost-effective screening and diagnostic tools into primary care, DAC aims to make substantial strides against Alzheimer’s, particularly within underrepresented Global South populations.

With Alzheimer’s projected to impact over 150 million families globally by 2050, DAC’s initiatives stand as a beacon of hope. Their work underscores the critical importance of early detection and nuanced care in addressing the growing global dementia crisis.

For more information on DAC’s transformative projects and partnerships, please visit their official website.