{"id":7630,"date":"2024-10-16T18:43:30","date_gmt":"2024-10-16T18:43:30","guid":{"rendered":"https:\/\/www.tun.com\/home\/?p=7630"},"modified":"2025-03-24T13:27:14","modified_gmt":"2025-03-24T13:27:14","slug":"ucf-researchers-develop-revolutionary-antibacterial-bandage-to-stop-severe-bleeding","status":"publish","type":"post","link":"https:\/\/www.tun.com\/home\/ucf-researchers-develop-revolutionary-antibacterial-bandage-to-stop-severe-bleeding\/","title":{"rendered":"UCF Researchers Develop Revolutionary Antibacterial Bandage to Stop Severe Bleeding"},"content":{"rendered":"\n<div class=\"wp-block-group\"><div class=\"wp-block-group__inner-container is-layout-constrained wp-block-group-is-layout-constrained\">\n<div class=\"wp-block-uagb-blockquote uagb-block-e7eb3fc3 uagb-blockquote__skin-border uagb-blockquote__stack-img-none\"><blockquote class=\"uagb-blockquote\"><div class=\"uagb-blockquote__content\">University of Central Florida researchers have developed SilFoam, an innovative bandage that rapidly stops severe bleeding and prevents infections, offering a new hope for trauma victims.<\/div><footer><div class=\"uagb-blockquote__author-wrap uagb-blockquote__author-at-left\"><\/div><\/footer><\/blockquote><\/div>\n\n\n\n<div class=\"wp-block-group is-content-justification-space-between is-nowrap is-layout-flex wp-container-core-group-is-layout-b0ffac9c wp-block-group-is-layout-flex\"><div style=\"font-size:16px\" class=\"has-text-align-left wp-block-post-author\"><div class=\"wp-block-post-author__content\"><p class=\"wp-block-post-author__name\">The University Network<\/p><\/div><\/div>\n\n\n<div class=\"wp-block-uagb-social-share uagb-social-share__outer-wrap uagb-social-share__layout-horizontal uagb-block-ee584a31\">\n<div class=\"wp-block-uagb-social-share-child uagb-ss-repeater uagb-ss__wrapper uagb-block-ec619ce7\"><span class=\"uagb-ss__link\" data-href=\"https:\/\/www.facebook.com\/sharer.php?u=\" tabindex=\"0\" role=\"button\" aria-label=\"facebook\"><span class=\"uagb-ss__source-wrap\"><span class=\"uagb-ss__source-icon\"><svg xmlns=\"https:\/\/www.w3.org\/2000\/svg\" viewBox=\"0 0 512 512\"><path d=\"M504 256C504 119 393 8 256 8S8 119 8 256c0 123.8 90.69 226.4 209.3 245V327.7h-63V256h63v-54.64c0-62.15 37-96.48 93.67-96.48 27.14 0 55.52 4.84 55.52 4.84v61h-31.28c-30.8 0-40.41 19.12-40.41 38.73V256h68.78l-11 71.69h-57.78V501C413.3 482.4 504 379.8 504 256z\"><\/path><\/svg><\/span><\/span><\/span><\/div>\n\n\n\n<div class=\"wp-block-uagb-social-share-child uagb-ss-repeater uagb-ss__wrapper uagb-block-32d99934\"><span class=\"uagb-ss__link\" data-href=\"https:\/\/twitter.com\/share?url=\" tabindex=\"0\" role=\"button\" aria-label=\"twitter\"><span class=\"uagb-ss__source-wrap\"><span class=\"uagb-ss__source-icon\"><svg xmlns=\"https:\/\/www.w3.org\/2000\/svg\" viewBox=\"0 0 512 512\"><path d=\"M389.2 48h70.6L305.6 224.2 487 464H345L233.7 318.6 106.5 464H35.8L200.7 275.5 26.8 48H172.4L272.9 180.9 389.2 48zM364.4 421.8h39.1L151.1 88h-42L364.4 421.8z\"><\/path><\/svg><\/span><\/span><\/span><\/div>\n\n\n\n<div class=\"wp-block-uagb-social-share-child uagb-ss-repeater uagb-ss__wrapper uagb-block-1d136f14\"><span class=\"uagb-ss__link\" data-href=\"https:\/\/www.linkedin.com\/shareArticle?url=\" tabindex=\"0\" role=\"button\" aria-label=\"linkedin\"><span class=\"uagb-ss__source-wrap\"><span class=\"uagb-ss__source-icon\"><svg xmlns=\"https:\/\/www.w3.org\/2000\/svg\" viewBox=\"0 0 448 512\"><path d=\"M416 32H31.9C14.3 32 0 46.5 0 64.3v383.4C0 465.5 14.3 480 31.9 480H416c17.6 0 32-14.5 32-32.3V64.3c0-17.8-14.4-32.3-32-32.3zM135.4 416H69V202.2h66.5V416zm-33.2-243c-21.3 0-38.5-17.3-38.5-38.5S80.9 96 102.2 96c21.2 0 38.5 17.3 38.5 38.5 0 21.3-17.2 38.5-38.5 38.5zm282.1 243h-66.4V312c0-24.8-.5-56.7-34.5-56.7-34.6 0-39.9 27-39.9 54.9V416h-66.4V202.2h63.7v29.2h.9c8.9-16.8 30.6-34.5 62.9-34.5 67.2 0 79.7 44.3 79.7 101.9V416z\"><\/path><\/svg><\/span><\/span><\/span><\/div>\n<\/div>\n<\/div>\n<\/div><\/div>\n\n\n\n<p class=\"wp-block-paragraph\"><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">University of Central Florida researchers have unveiled a groundbreaking medical advancement that could drastically improve survival rates in severe bleeding incidents. The newly developed hemostatic sponge-like bandage, dubbed &#8220;SilFoam,&#8221; promises not only to staunch bleeding quickly but also to combat infections effectively.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u201cWhat happens in the field or during an accident is due to heavy bleeding, patients can die,\u201d co-author Kausik Mukhopadhyay, an assistant professor of materials science and engineering at UCF, said in a <a href=\"https:\/\/www.ucf.edu\/news\/life-saving-spongelike-bandage-developed-by-ucf-researchers-rapidly-stops-hemorrhaging-and-mitigates-risk-of-infection\/\">news release<\/a>. \u201cThese fatalities usually occur in the first 30 minutes to one hour. Our whole idea was to develop a very simple solution that could have the hemostatic efficacy within that time.\u201d<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><\/p>\n\n\n\n<div style=\"height:16px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<figure class=\"wp-block-embed aligncenter is-type-video is-provider-youtube wp-block-embed-youtube wp-embed-aspect-16-9 wp-has-aspect-ratio\"><div class=\"wp-block-embed__wrapper\">\n<iframe loading=\"lazy\" title=\"Life Saving Foam Stops Bleeding\" width=\"500\" height=\"281\" src=\"https:\/\/www.youtube.com\/embed\/PCAeR76L3T0?feature=oembed\" frameborder=\"0\" allow=\"accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture; web-share\" referrerpolicy=\"strict-origin-when-cross-origin\" allowfullscreen><\/iframe>\n<\/div><\/figure>\n\n\n\n<div style=\"height:7px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading\">Innovative Chemistry and Mechanisms<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">SilFoam operates differently than traditional bandages. Comprised of siloxanes (silicon and oxygen), it is delivered as a liquid gel through a special two-chamber syringe. Once injected, it transforms into a voluminous sponge within the wound in under one minute. This expansion exerts pressure to control bleeding while silver oxide provides antimicrobial properties.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Mukhopadhyay explains that for every 5 milliliters of gel injected, the expansion achieves about 35 milliliters in volume. <\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u201cAnytime you have a profuse bleeding or bleeding, you want to press on top and stop the bleeding. So, what we did here is actually the same thing. Instead of putting the hand, we injected it, and it creates a voluminous expansion,\u201d he added.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The sponge&#8217;s adhesive and porous characteristics were optimized to prevent further injury during removal. <\/p>\n\n\n\n<p class=\"wp-block-paragraph\">&#8220;The adhesive property of this bandage is optimized so that when you take it out from the system, the smaller vessels don\u2019t get ruptured, but it has the right amount of adhesion that can adhere to the muscles, veins and arteries so that the blood doesn\u2019t leak,&#8221; Mukhopadhyay added.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Groundbreaking Experimentation<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">To test their innovation, the researchers used anatomically accurate mannequins designed with realistic blood vessels and wounds by local company SIMETRI. This non-invasive testing was crucial in determining the potential of SilFoam before moving to live model studies.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The effectiveness of SilFoam was compared to five existing treatment methods, showcasing significant advantages, including less leakage, room-temperature storage, lower cost and minimal training requirements.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Pritha Sarkar, a graduate student at UCF who contributed significantly to the experimentation, emphasized the importance of balancing the material&#8217;s reactivity with safety. <\/p>\n\n\n\n<p class=\"wp-block-paragraph\">&#8220;We had to check the reactivity of the two parts because we wanted enough oxygen gas that can expand the sponge, but at the same time, we didn\u2019t want the material to get too hot,&#8221; she said in the news release.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Combating Infections<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">SilFoam was also tested for its antimicrobial properties under the stewardship of Melanie Coathup, a professor at UCF College of Medicine and director of the Biionix Cluster. Their collaborative findings were promising.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u201cMy post-doc Dr. Abi Sindu Pugazhendhi and I worked alongside Dr. Mukhopadhyay and team to investigate the potency of his material and how well it stopped bacterial growth,\u201d Coathup said. \u201cWe assessed bacteria that would typically infect a traumatic injury to the torso, and our results showed that the material was highly effective.\u201d<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">&#8220;We have a dressing that can expand onto your wound and seal it shut,&#8221; added Sarkar, &#8220;but at the same time, once it\u2019s done its job, you can remove it very easily.\u201d<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Next Steps and Future Implications<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Mukhopadhyay has received a GAP award to assist in the licensing and deployment of SilFoam. The next phase involves collaboration with the University of Nebraska Medical Center to conduct in vivo studies.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">As the research progresses, the potential impact of SilFoam in emergency medicine is immense. From military combat zones to civilian accidents, this life-saving technology promises to be a game changer. For now, the researchers continue their work, driven by the goal of saving lives and reducing the risk of fatal hemorrhaging on the battlefield and beyond.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><\/p>\n","protected":false},"excerpt":{"rendered":"<p>University of Central Florida researchers have unveiled a groundbreaking medical advancement that could drastically improve survival rates in severe bleeding incidents. The newly developed hemostatic sponge-like bandage, dubbed &#8220;SilFoam,&#8221; promises not only to staunch bleeding quickly but also to combat infections effectively. \u201cWhat happens in the field or during an accident is due to heavy [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"single-no-separators","format":"standard","meta":{"_acf_changed":false,"_uag_custom_page_level_css":"","_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":""},"categories":[25],"tags":[],"class_list":["post-7630","post","type-post","status-publish","format-standard","hentry","category-science"],"acf":[],"aioseo_notices":[],"uagb_featured_image_src":{"full":false,"thumbnail":false,"medium":false,"medium_large":false,"large":false,"1536x1536":false,"2048x2048":false},"uagb_author_info":{"display_name":"The University Network","author_link":"https:\/\/www.tun.com\/home\/author\/funky_junkie\/"},"uagb_comment_info":0,"uagb_excerpt":"University of Central Florida researchers have unveiled a groundbreaking medical advancement that could drastically improve survival rates in severe bleeding incidents. The newly developed hemostatic sponge-like bandage, dubbed &#8220;SilFoam,&#8221; promises not only to staunch bleeding quickly but also to combat infections effectively. \u201cWhat happens in the field or during an accident is due to heavy&hellip;","_links":{"self":[{"href":"https:\/\/www.tun.com\/home\/wp-json\/wp\/v2\/posts\/7630","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.tun.com\/home\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.tun.com\/home\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.tun.com\/home\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/www.tun.com\/home\/wp-json\/wp\/v2\/comments?post=7630"}],"version-history":[{"count":9,"href":"https:\/\/www.tun.com\/home\/wp-json\/wp\/v2\/posts\/7630\/revisions"}],"predecessor-version":[{"id":20650,"href":"https:\/\/www.tun.com\/home\/wp-json\/wp\/v2\/posts\/7630\/revisions\/20650"}],"wp:attachment":[{"href":"https:\/\/www.tun.com\/home\/wp-json\/wp\/v2\/media?parent=7630"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.tun.com\/home\/wp-json\/wp\/v2\/categories?post=7630"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.tun.com\/home\/wp-json\/wp\/v2\/tags?post=7630"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}