{"id":3629,"date":"2024-08-19T17:29:19","date_gmt":"2024-08-19T17:29:19","guid":{"rendered":"https:\/\/www.tun.com\/home\/?p=3629"},"modified":"2024-10-16T21:23:36","modified_gmt":"2024-10-16T21:23:36","slug":"revolutionary-saliva-test-for-heart-failure-offers-hope-for-remote-communities","status":"publish","type":"post","link":"https:\/\/www.tun.com\/home\/revolutionary-saliva-test-for-heart-failure-offers-hope-for-remote-communities\/","title":{"rendered":"Revolutionary Saliva Test for Heart Failure Offers Hope for Remote Communities"},"content":{"rendered":"\n<div class=\"wp-block-group\"><div class=\"wp-block-group__inner-container is-layout-constrained wp-block-group-is-layout-constrained\">\n<div class=\"wp-block-uagb-blockquote uagb-block-e7eb3fc3 uagb-blockquote__skin-border uagb-blockquote__stack-img-none\"><blockquote class=\"uagb-blockquote\"><div class=\"uagb-blockquote__content\">Scientists from Colorado State University and Griffith University have developed a simple, cost-effective biosensor that can detect heart failure biomarkers from a drop of saliva within 15 minutes. This innovation promises to revolutionize health care accessibility for remote and underserved populations.<\/div><footer><div class=\"uagb-blockquote__author-wrap uagb-blockquote__author-at-left\"><\/div><\/footer><\/blockquote><\/div>\n\n\n\n<div class=\"wp-block-group is-content-justification-space-between is-nowrap is-layout-flex wp-container-core-group-is-layout-b0ffac9c wp-block-group-is-layout-flex\"><div style=\"font-size:16px\" class=\"has-text-align-left wp-block-post-author\"><div class=\"wp-block-post-author__content\"><p class=\"wp-block-post-author__name\">The University Network<\/p><\/div><\/div>\n\n\n<div class=\"wp-block-uagb-social-share uagb-social-share__outer-wrap uagb-social-share__layout-horizontal uagb-block-ee584a31\">\n<div class=\"wp-block-uagb-social-share-child uagb-ss-repeater uagb-ss__wrapper uagb-block-ec619ce7\"><span class=\"uagb-ss__link\" data-href=\"https:\/\/www.facebook.com\/sharer.php?u=\" tabindex=\"0\" role=\"button\" aria-label=\"facebook\"><span class=\"uagb-ss__source-wrap\"><span class=\"uagb-ss__source-icon\"><svg xmlns=\"https:\/\/www.w3.org\/2000\/svg\" viewBox=\"0 0 512 512\"><path d=\"M504 256C504 119 393 8 256 8S8 119 8 256c0 123.8 90.69 226.4 209.3 245V327.7h-63V256h63v-54.64c0-62.15 37-96.48 93.67-96.48 27.14 0 55.52 4.84 55.52 4.84v61h-31.28c-30.8 0-40.41 19.12-40.41 38.73V256h68.78l-11 71.69h-57.78V501C413.3 482.4 504 379.8 504 256z\"><\/path><\/svg><\/span><\/span><\/span><\/div>\n\n\n\n<div class=\"wp-block-uagb-social-share-child uagb-ss-repeater uagb-ss__wrapper uagb-block-32d99934\"><span class=\"uagb-ss__link\" data-href=\"https:\/\/twitter.com\/share?url=\" tabindex=\"0\" role=\"button\" aria-label=\"twitter\"><span class=\"uagb-ss__source-wrap\"><span class=\"uagb-ss__source-icon\"><svg xmlns=\"https:\/\/www.w3.org\/2000\/svg\" viewBox=\"0 0 512 512\"><path d=\"M389.2 48h70.6L305.6 224.2 487 464H345L233.7 318.6 106.5 464H35.8L200.7 275.5 26.8 48H172.4L272.9 180.9 389.2 48zM364.4 421.8h39.1L151.1 88h-42L364.4 421.8z\"><\/path><\/svg><\/span><\/span><\/span><\/div>\n\n\n\n<div class=\"wp-block-uagb-social-share-child uagb-ss-repeater uagb-ss__wrapper uagb-block-1d136f14\"><span class=\"uagb-ss__link\" data-href=\"https:\/\/www.linkedin.com\/shareArticle?url=\" tabindex=\"0\" role=\"button\" aria-label=\"linkedin\"><span class=\"uagb-ss__source-wrap\"><span class=\"uagb-ss__source-icon\"><svg xmlns=\"https:\/\/www.w3.org\/2000\/svg\" viewBox=\"0 0 448 512\"><path d=\"M416 32H31.9C14.3 32 0 46.5 0 64.3v383.4C0 465.5 14.3 480 31.9 480H416c17.6 0 32-14.5 32-32.3V64.3c0-17.8-14.4-32.3-32-32.3zM135.4 416H69V202.2h66.5V416zm-33.2-243c-21.3 0-38.5-17.3-38.5-38.5S80.9 96 102.2 96c21.2 0 38.5 17.3 38.5 38.5 0 21.3-17.2 38.5-38.5 38.5zm282.1 243h-66.4V312c0-24.8-.5-56.7-34.5-56.7-34.6 0-39.9 27-39.9 54.9V416h-66.4V202.2h63.7v29.2h.9c8.9-16.8 30.6-34.5 62.9-34.5 67.2 0 79.7 44.3 79.7 101.9V416z\"><\/path><\/svg><\/span><\/span><\/span><\/div>\n<\/div>\n<\/div>\n<\/div><\/div>\n\n\n\n<p class=\"wp-block-paragraph\">Heart failure remains one of the leading causes of death worldwide, disproportionately affecting those with limited access to medical facilities. In a groundbreaking effort to address this issue, a team of researchers has developed a novel electrochemical biosensor prototype designed to detect heart failure biomarkers using just a drop of saliva.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Trey Pittman, a graduate student at Colorado State University, will present his team\u2019s innovative research at the American Chemical Society&#8217;s Fall 2024 meeting. Their device, which resembles a COVID-19 lateral flow test, promises rapid, point-of-care heart failure screening within 15 minutes.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u201cOur device would be ideal for people who are at high risk for heart failure but have limited access to a hospital or a centralized lab,\u201d Pittman said in a <a href=\"https:\/\/www.acs.org\/pressroom\/presspacs\/2024\/august\/improving-access-to-heart-failure-screening-with-saliva.html\" title=\"\">news release<\/a>. \u201cWorking on this project to address health disparities in rural and low-resource areas really hits home for me because I\u2019m from Mississippi, which has one of the highest mortality rates from heart failure in the United States.\u201d<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Heart failure, characterized by a weakened heart muscle that cannot effectively pump blood, is traditionally diagnosed through a blood test that measures B-type natriuretic peptide (BNP). This test typically requires biannual hospital visits, which are not accessible to everyone. <\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The new saliva-based test, however, could be administered by patients themselves more frequently.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">One of the standout features of this device, known as an electrochemical capillary-driven immunoassay (eCaDI), is its simplicity and affordability. The eCaDI uses five layers of clear, flexible plastic, with laser-cut channels and blotting paper to draw saliva from the sample site. Electrodes on the device help measure two crucial biomarkers \u2014 Galectin-3 and S100A7.<\/p>\n\n\n\n<div style=\"height:13px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<figure class=\"wp-block-embed aligncenter is-type-video is-provider-youtube wp-block-embed-youtube wp-embed-aspect-16-9 wp-has-aspect-ratio\"><div class=\"wp-block-embed__wrapper\">\n<iframe loading=\"lazy\" title=\"Saliva test gives heart failure prognosis on demand | Headline Science\" width=\"500\" height=\"281\" src=\"https:\/\/www.youtube.com\/embed\/oo_h71ZHreQ?feature=oembed\" frameborder=\"0\" allow=\"accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture; web-share\" referrerpolicy=\"strict-origin-when-cross-origin\" allowfullscreen><\/iframe>\n<\/div><\/figure>\n\n\n\n<div style=\"height:8px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p class=\"wp-block-paragraph\">\u201cThe devices are very easy to assemble,\u201d added Pittman. \u201cIn about 20 to 30 minutes, we can make five of them.\u201d<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Each unit costs approximately $3.00, while the reusable power source, a potentiostat, sells for about $20.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Demonstrations have already shown that the eCaDI can accurately measure the levels of Galectin-3 and S100A7 in standardized saliva samples, indicating heart failure. <\/p>\n\n\n\n<p class=\"wp-block-paragraph\">These initial tests are a promising step towards a reliable, non-invasive and cost-effective method for heart failure screening.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Heart failure remains one of the leading causes of death worldwide, disproportionately affecting those with limited access to medical facilities. In a groundbreaking effort to address this issue, a team of researchers has developed a novel electrochemical biosensor prototype designed to detect heart failure biomarkers using just a drop of saliva. Trey Pittman, a graduate [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"single-no-separators","format":"standard","meta":{"_acf_changed":false,"_uag_custom_page_level_css":"","_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":""},"categories":[12],"tags":[],"class_list":["post-3629","post","type-post","status-publish","format-standard","hentry","category-health"],"acf":[],"aioseo_notices":[],"uagb_featured_image_src":{"full":false,"thumbnail":false,"medium":false,"medium_large":false,"large":false,"1536x1536":false,"2048x2048":false},"uagb_author_info":{"display_name":"The University Network","author_link":"https:\/\/www.tun.com\/home\/author\/funky_junkie\/"},"uagb_comment_info":0,"uagb_excerpt":"Heart failure remains one of the leading causes of death worldwide, disproportionately affecting those with limited access to medical facilities. In a groundbreaking effort to address this issue, a team of researchers has developed a novel electrochemical biosensor prototype designed to detect heart failure biomarkers using just a drop of saliva. Trey Pittman, a graduate&hellip;","_links":{"self":[{"href":"https:\/\/www.tun.com\/home\/wp-json\/wp\/v2\/posts\/3629","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.tun.com\/home\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.tun.com\/home\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.tun.com\/home\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/www.tun.com\/home\/wp-json\/wp\/v2\/comments?post=3629"}],"version-history":[{"count":7,"href":"https:\/\/www.tun.com\/home\/wp-json\/wp\/v2\/posts\/3629\/revisions"}],"predecessor-version":[{"id":3744,"href":"https:\/\/www.tun.com\/home\/wp-json\/wp\/v2\/posts\/3629\/revisions\/3744"}],"wp:attachment":[{"href":"https:\/\/www.tun.com\/home\/wp-json\/wp\/v2\/media?parent=3629"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.tun.com\/home\/wp-json\/wp\/v2\/categories?post=3629"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.tun.com\/home\/wp-json\/wp\/v2\/tags?post=3629"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}