{"id":32065,"date":"2025-12-08T21:34:26","date_gmt":"2025-12-08T21:34:26","guid":{"rendered":"https:\/\/www.tun.com\/home\/?p=32065"},"modified":"2025-12-08T21:34:29","modified_gmt":"2025-12-08T21:34:29","slug":"blood-tests-for-cancer-detection-a-step-closer-to-reality-say-scientists","status":"publish","type":"post","link":"https:\/\/www.tun.com\/home\/blood-tests-for-cancer-detection-a-step-closer-to-reality-say-scientists\/","title":{"rendered":"Blood Tests for Cancer Detection: A Step Closer to Reality, Say Scientists"},"content":{"rendered":"\n<div class=\"wp-block-group\"><div class=\"wp-block-group__inner-container is-layout-constrained wp-block-group-is-layout-constrained\">\n<div class=\"wp-block-uagb-blockquote uagb-block-e7eb3fc3 uagb-blockquote__skin-border uagb-blockquote__stack-img-none\"><blockquote class=\"uagb-blockquote\"><div class=\"uagb-blockquote__content\">University of Sharjah researchers highlight how AI-assisted blood tests using exosome analysis could revolutionize cancer detection and treatment, offering a non-invasive, early-detection method.<\/div><footer><div class=\"uagb-blockquote__author-wrap uagb-blockquote__author-at-left\"><\/div><\/footer><\/blockquote><\/div>\n\n\n\n<div class=\"wp-block-group is-content-justification-space-between is-nowrap is-layout-flex wp-container-core-group-is-layout-b0ffac9c wp-block-group-is-layout-flex\"><div style=\"font-size:16px\" class=\"has-text-align-left wp-block-post-author\"><div class=\"wp-block-post-author__content\"><p class=\"wp-block-post-author__name\">The University Network<\/p><\/div><\/div>\n\n\n<div class=\"wp-block-uagb-social-share uagb-social-share__outer-wrap uagb-social-share__layout-horizontal uagb-block-ee584a31\">\n<div class=\"wp-block-uagb-social-share-child uagb-ss-repeater uagb-ss__wrapper uagb-block-ec619ce7\"><span class=\"uagb-ss__link\" data-href=\"https:\/\/www.facebook.com\/sharer.php?u=\" tabindex=\"0\" role=\"button\" aria-label=\"facebook\"><span class=\"uagb-ss__source-wrap\"><span class=\"uagb-ss__source-icon\"><svg xmlns=\"https:\/\/www.w3.org\/2000\/svg\" viewBox=\"0 0 512 512\"><path d=\"M504 256C504 119 393 8 256 8S8 119 8 256c0 123.8 90.69 226.4 209.3 245V327.7h-63V256h63v-54.64c0-62.15 37-96.48 93.67-96.48 27.14 0 55.52 4.84 55.52 4.84v61h-31.28c-30.8 0-40.41 19.12-40.41 38.73V256h68.78l-11 71.69h-57.78V501C413.3 482.4 504 379.8 504 256z\"><\/path><\/svg><\/span><\/span><\/span><\/div>\n\n\n\n<div class=\"wp-block-uagb-social-share-child uagb-ss-repeater uagb-ss__wrapper uagb-block-32d99934\"><span class=\"uagb-ss__link\" data-href=\"https:\/\/twitter.com\/share?url=\" tabindex=\"0\" role=\"button\" aria-label=\"twitter\"><span class=\"uagb-ss__source-wrap\"><span class=\"uagb-ss__source-icon\"><svg xmlns=\"https:\/\/www.w3.org\/2000\/svg\" viewBox=\"0 0 512 512\"><path d=\"M389.2 48h70.6L305.6 224.2 487 464H345L233.7 318.6 106.5 464H35.8L200.7 275.5 26.8 48H172.4L272.9 180.9 389.2 48zM364.4 421.8h39.1L151.1 88h-42L364.4 421.8z\"><\/path><\/svg><\/span><\/span><\/span><\/div>\n\n\n\n<div class=\"wp-block-uagb-social-share-child uagb-ss-repeater uagb-ss__wrapper uagb-block-1d136f14\"><span class=\"uagb-ss__link\" data-href=\"https:\/\/www.linkedin.com\/shareArticle?url=\" tabindex=\"0\" role=\"button\" aria-label=\"linkedin\"><span class=\"uagb-ss__source-wrap\"><span class=\"uagb-ss__source-icon\"><svg xmlns=\"https:\/\/www.w3.org\/2000\/svg\" viewBox=\"0 0 448 512\"><path d=\"M416 32H31.9C14.3 32 0 46.5 0 64.3v383.4C0 465.5 14.3 480 31.9 480H416c17.6 0 32-14.5 32-32.3V64.3c0-17.8-14.4-32.3-32-32.3zM135.4 416H69V202.2h66.5V416zm-33.2-243c-21.3 0-38.5-17.3-38.5-38.5S80.9 96 102.2 96c21.2 0 38.5 17.3 38.5 38.5 0 21.3-17.2 38.5-38.5 38.5zm282.1 243h-66.4V312c0-24.8-.5-56.7-34.5-56.7-34.6 0-39.9 27-39.9 54.9V416h-66.4V202.2h63.7v29.2h.9c8.9-16.8 30.6-34.5 62.9-34.5 67.2 0 79.7 44.3 79.7 101.9V416z\"><\/path><\/svg><\/span><\/span><\/span><\/div>\n<\/div>\n<\/div>\n<\/div><\/div>\n\n\n\n<p class=\"wp-block-paragraph\">Imagine detecting cancer through a simple blood or urine test instead of invasive biopsies. This vision is becoming increasingly realistic, thanks to breakthrough research on exosomes \u2014 tiny particles released by cells carrying molecular signatures of cancer.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Scientists from the University of Sharjah, led by Mohammad Harb&nbsp;Semreen, a professor of pharmaceutical chemistry, have highlighted the potential of this method through an extensive narrative review <a href=\"https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S0009898125004851\" target=\"_blank\" rel=\"noopener\" title=\"\">published<\/a> in the Clinica Chimica Acta journal. The review, which encompassed over 100 studies published between 2018 and 2025, shows that an AI-assisted blood or urine test could soon offer a quicker, non-invasive method for diagnosing cancer.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u201cBy decoding the molecular \u2018cargo\u2019 of these exosomes through a multi-omics approach\u2014combining proteomics, transcriptomics, metabolomics, and lipidomics\u2014we can build a detailed map of how cancers communicate, grow, and evade treatment,\u201d Semreen said in a news release. \u201cThis gives researchers a new way to discover precise, reliable biomarkers that can detect cancer earlier, predict how aggressive it might become, and monitor how patients respond to therapy.\u201d<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Exosomes, the microscopic messengers involved in this process, undergo significant changes in cancer. These changes include being loaded with proteins, genetic material, lipids and metabolites that mirror the tumor&#8217;s condition. <\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Current advancements in artificial intelligence are enhancing the ability to scan vast molecular datasets, revealing patterns and aiding in the discovery of reliable cancer biomarkers.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Semreen describes this exosome-based approach as \u201cpowerful\u201d because \u201cexosomes can be collected from simple body fluids such as blood or urine, meaning that one day cancer could be tracked through a non-invasive liquid biopsy instead of painful tissue samples.\u201d<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The potential impact of this research is profound. According to the&nbsp;<a href=\"https:\/\/www.who.int\/news\/item\/01-02-2024-global-cancer-burden-growing--amidst-mounting-need-for-services\" target=\"_blank\" rel=\"noopener\" title=\"\">International Agency for Research on Cancer<\/a> (IARC), nearly 10 million deaths were caused by cancer in 2022, with around 20 million new cases reported. The disease&#8217;s sheer scale makes early detection crucial for improving treatment outcomes and patient survival.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u201cExosomes carry the whispers of cancer cells\u2014we\u2019re learning how to listen. By decoding exosomes, we can catch cancer earlier and treat it more intelligently,&#8221; added lead author Fatima Maher Al-Daffaie, a PhD candidate in drug design and discovery at the University of Sharjah\u2019s College of Pharmacy. \u201cOur aim is to turn a simple blood test into a powerful diagnostic tool. These nano-messengers give us a real-time view of what\u2019s happening inside tumors. What once required surgery may soon be done with a drop of blood.\u201d<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The implications of this research extend beyond detection. Exosomes could also be engineered to transport treatments directly to tumor cells, improving precision and reducing side effects. <\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u201cThese nanoscale vesicles can be engineered to transport anti-cancer drugs, RNA molecules, or even gene-editing tools directly to tumor cells. Their natural compatibility with the human body means they can deliver treatments precisely where needed, reducing side effects and enhancing efficacy,\u201d Semreen added.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Co-author Ahmad Abuhelwa, an associate professor of clinical pharmacology and pharmacometrics, noted the research&#8217;s potential to revolutionize cancer diagnostics. <\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u201cExosomes offer a living snapshot of cancer\u2019s behavior. By analyzing their molecular signatures, we can personalize treatment and monitor how each patient\u2019s tumor evolves over time,&#8221; he said in the news release. &#8220;By integrating multi-omics data and artificial intelligence, we can interpret the vast complexity of cancer biology in a way that is clinically actionable. This is a step toward making precision oncology not just a concept, but a reality in routine medical care.\u201d<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">While the study has not yet led to formal collaborations with industry or health care institutions, the field of exosome-based diagnostics is rapidly gaining global attention and investment from biotechnology and pharmaceutical companies.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u201cAs our work continues to bridge discovery science with clinical applications, we expect new partnerships to form\u2014particularly with companies and research institutes interested in developing next-generation cancer diagnostics and personalized monitoring tools,\u201d added Semreen.<\/p>\n\n\n\n<div style=\"height:9px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Source: <\/strong><a href=\"https:\/\/www.eurekalert.org\/news-releases\/1108121\" target=\"_blank\" rel=\"noopener\" title=\"\">University of Sharjah<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Imagine detecting cancer through a simple blood or urine test instead of invasive biopsies. This vision is becoming increasingly realistic, thanks to breakthrough research on exosomes \u2014 tiny particles released by cells carrying molecular signatures of cancer. Scientists from the University of Sharjah, led by Mohammad Harb&nbsp;Semreen, a professor of pharmaceutical chemistry, have highlighted the [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"single-no-separators","format":"standard","meta":{"_acf_changed":false,"_uag_custom_page_level_css":"","_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":""},"categories":[25],"tags":[171],"class_list":["post-32065","post","type-post","status-publish","format-standard","hentry","category-science","tag-university-of-sharjah"],"acf":[],"aioseo_notices":[],"uagb_featured_image_src":{"full":false,"thumbnail":false,"medium":false,"medium_large":false,"large":false,"1536x1536":false,"2048x2048":false},"uagb_author_info":{"display_name":"The University Network","author_link":"https:\/\/www.tun.com\/home\/author\/funky_junkie\/"},"uagb_comment_info":0,"uagb_excerpt":"Imagine detecting cancer through a simple blood or urine test instead of invasive biopsies. This vision is becoming increasingly realistic, thanks to breakthrough research on exosomes \u2014 tiny particles released by cells carrying molecular signatures of cancer. Scientists from the University of Sharjah, led by Mohammad Harb&nbsp;Semreen, a professor of pharmaceutical chemistry, have highlighted the&hellip;","_links":{"self":[{"href":"https:\/\/www.tun.com\/home\/wp-json\/wp\/v2\/posts\/32065","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.tun.com\/home\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.tun.com\/home\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.tun.com\/home\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/www.tun.com\/home\/wp-json\/wp\/v2\/comments?post=32065"}],"version-history":[{"count":11,"href":"https:\/\/www.tun.com\/home\/wp-json\/wp\/v2\/posts\/32065\/revisions"}],"predecessor-version":[{"id":32079,"href":"https:\/\/www.tun.com\/home\/wp-json\/wp\/v2\/posts\/32065\/revisions\/32079"}],"wp:attachment":[{"href":"https:\/\/www.tun.com\/home\/wp-json\/wp\/v2\/media?parent=32065"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.tun.com\/home\/wp-json\/wp\/v2\/categories?post=32065"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.tun.com\/home\/wp-json\/wp\/v2\/tags?post=32065"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}