{"id":30932,"date":"2025-10-22T14:27:16","date_gmt":"2025-10-22T14:27:16","guid":{"rendered":"https:\/\/www.tun.com\/home\/?p=30932"},"modified":"2025-10-22T14:27:18","modified_gmt":"2025-10-22T14:27:18","slug":"gut-bacteria-discovery-offers-hope-for-a-new-ibs-treatment","status":"publish","type":"post","link":"https:\/\/www.tun.com\/home\/gut-bacteria-discovery-offers-hope-for-a-new-ibs-treatment\/","title":{"rendered":"Gut Bacteria Discovery Offers Hope for a New IBS Treatment"},"content":{"rendered":"\n<div class=\"wp-block-group\"><div class=\"wp-block-group__inner-container is-layout-constrained wp-block-group-is-layout-constrained\">\n<div class=\"wp-block-uagb-blockquote uagb-block-e7eb3fc3 uagb-blockquote__skin-border uagb-blockquote__stack-img-none\"><blockquote class=\"uagb-blockquote\"><div class=\"uagb-blockquote__content\">Scientists from the University of Gothenburg have discovered that specific gut bacteria can produce serotonin, potentially leading to new treatments for Irritable Bowel Syndrome (IBS). <\/div><footer><div class=\"uagb-blockquote__author-wrap uagb-blockquote__author-at-left\"><\/div><\/footer><\/blockquote><\/div>\n\n\n\n<div class=\"wp-block-group is-content-justification-space-between is-nowrap is-layout-flex wp-container-core-group-is-layout-b0ffac9c wp-block-group-is-layout-flex\"><div style=\"font-size:16px\" class=\"has-text-align-left wp-block-post-author\"><div class=\"wp-block-post-author__content\"><p class=\"wp-block-post-author__name\">The University Network<\/p><\/div><\/div>\n\n\n<div class=\"wp-block-uagb-social-share uagb-social-share__outer-wrap uagb-social-share__layout-horizontal uagb-block-ee584a31\">\n<div class=\"wp-block-uagb-social-share-child uagb-ss-repeater uagb-ss__wrapper uagb-block-ec619ce7\"><span class=\"uagb-ss__link\" data-href=\"https:\/\/www.facebook.com\/sharer.php?u=\" tabindex=\"0\" role=\"button\" aria-label=\"facebook\"><span class=\"uagb-ss__source-wrap\"><span class=\"uagb-ss__source-icon\"><svg xmlns=\"https:\/\/www.w3.org\/2000\/svg\" viewBox=\"0 0 512 512\"><path d=\"M504 256C504 119 393 8 256 8S8 119 8 256c0 123.8 90.69 226.4 209.3 245V327.7h-63V256h63v-54.64c0-62.15 37-96.48 93.67-96.48 27.14 0 55.52 4.84 55.52 4.84v61h-31.28c-30.8 0-40.41 19.12-40.41 38.73V256h68.78l-11 71.69h-57.78V501C413.3 482.4 504 379.8 504 256z\"><\/path><\/svg><\/span><\/span><\/span><\/div>\n\n\n\n<div class=\"wp-block-uagb-social-share-child uagb-ss-repeater uagb-ss__wrapper uagb-block-32d99934\"><span class=\"uagb-ss__link\" data-href=\"https:\/\/twitter.com\/share?url=\" tabindex=\"0\" role=\"button\" aria-label=\"twitter\"><span class=\"uagb-ss__source-wrap\"><span class=\"uagb-ss__source-icon\"><svg xmlns=\"https:\/\/www.w3.org\/2000\/svg\" viewBox=\"0 0 512 512\"><path d=\"M389.2 48h70.6L305.6 224.2 487 464H345L233.7 318.6 106.5 464H35.8L200.7 275.5 26.8 48H172.4L272.9 180.9 389.2 48zM364.4 421.8h39.1L151.1 88h-42L364.4 421.8z\"><\/path><\/svg><\/span><\/span><\/span><\/div>\n\n\n\n<div class=\"wp-block-uagb-social-share-child uagb-ss-repeater uagb-ss__wrapper uagb-block-1d136f14\"><span class=\"uagb-ss__link\" data-href=\"https:\/\/www.linkedin.com\/shareArticle?url=\" tabindex=\"0\" role=\"button\" aria-label=\"linkedin\"><span class=\"uagb-ss__source-wrap\"><span class=\"uagb-ss__source-icon\"><svg xmlns=\"https:\/\/www.w3.org\/2000\/svg\" viewBox=\"0 0 448 512\"><path d=\"M416 32H31.9C14.3 32 0 46.5 0 64.3v383.4C0 465.5 14.3 480 31.9 480H416c17.6 0 32-14.5 32-32.3V64.3c0-17.8-14.4-32.3-32-32.3zM135.4 416H69V202.2h66.5V416zm-33.2-243c-21.3 0-38.5-17.3-38.5-38.5S80.9 96 102.2 96c21.2 0 38.5 17.3 38.5 38.5 0 21.3-17.2 38.5-38.5 38.5zm282.1 243h-66.4V312c0-24.8-.5-56.7-34.5-56.7-34.6 0-39.9 27-39.9 54.9V416h-66.4V202.2h63.7v29.2h.9c8.9-16.8 30.6-34.5 62.9-34.5 67.2 0 79.7 44.3 79.7 101.9V416z\"><\/path><\/svg><\/span><\/span><\/span><\/div>\n<\/div>\n<\/div>\n<\/div><\/div>\n\n\n\n<p class=\"wp-block-paragraph\">Research from the University of Gothenburg in Sweden sheds light on the intricacies between gut bacteria and Irritable Bowel Syndrome (IBS), potentially paving the way for innovative treatments. The study, <a href=\"https:\/\/www.cell.com\/cell-reports\/fulltext\/S2211-1247(25)01205-7\" target=\"_blank\" rel=\"noopener\" title=\"\">published<\/a> in the journal Cell Reports, reveals that certain gut bacteria can produce serotonin, a key substance in bowel function and mood regulation.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">IBS is a widespread gastrointestinal disorder, predominantly affecting women. Its symptoms include abdominal pain, constipation and diarrhea. <\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Although the exact cause remains elusive, the intestinal environment, particularly the gut microbiota and the neurotransmitter serotonin, plays a crucial role.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Serotonin is primarily known as a brain neurotransmitter, yet over 90% of the body&#8217;s serotonin is produced in the gut, where it regulates bowel movements through the enteric nervous system, often referred to as the &#8220;gut-brain.&#8221;<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">While prior research showed that gut microbiota impacts serotonin levels, it was unclear whether gut bacteria could directly produce biologically active serotonin. <\/p>\n\n\n\n<p class=\"wp-block-paragraph\">In this study, the researchers identified two bacteria, <em>Limosilactobacillus mucosae<\/em> and <em>Ligilactobacillus ruminis<\/em>, which can produce serotonin.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Experiments on germ-free mice with serotonin deficiency showed a marked increase in gut serotonin levels and a higher density of nerve cells in the colon when these bacteria were introduced. The bacteria effectively normalized intestinal transit time, suggesting improved bowel function.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u201cIt is incredibly fascinating how the gut bacteria can produce bioactive signaling molecules that affect health,\u201d Fredrik B\u00e4ckhed, a professor of molecular medicine at the University of Gothenburg&#8217;s Sahlgrenska Academy and one of the leading authors of the study, said in a news release.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The research also found that individuals with IBS had lower levels of <em>L. mucosae<\/em> in their stools compared to healthy individuals, indicating a potential link between this bacterium and IBS symptoms.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u201cOur results indicate that certain intestinal bacteria can produce bioactive serotonin and thus play an important role in intestinal health and open new avenues for the treatment of functional gastrointestinal disorders such as IBS,\u201d added Magnus Simr\u00e9n, a Sahlgrenska Academy professor of medical gastroenterology.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">This breakthrough underscores the critical role of gut microbiota in health and disease, offering new hope for effective IBS treatments and enhancing our understanding of the gut-brain connection.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">&#8220;Our findings indicate that intestinal bacteria can form signaling substances such as serotonin, which may be the key to understanding how the intestine and its inhabitants can affect our brain and behavior,&#8221; B\u00e4ckhed added. <\/p>\n\n\n\n<div style=\"height:12px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Source: <\/strong><a href=\"https:\/\/www.gu.se\/en\/news\/new-role-of-gut-bacteria-provides-hope-for-a-novel-ibs-treatment\" target=\"_blank\" rel=\"noopener\" title=\"\">University of Gothenburg<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Research from the University of Gothenburg in Sweden sheds light on the intricacies between gut bacteria and Irritable Bowel Syndrome (IBS), potentially paving the way for innovative treatments. The study, published in the journal Cell Reports, reveals that certain gut bacteria can produce serotonin, a key substance in bowel function and mood regulation. IBS is [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"single-no-separators","format":"standard","meta":{"_acf_changed":false,"_uag_custom_page_level_css":"","_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":""},"categories":[12],"tags":[169],"class_list":["post-30932","post","type-post","status-publish","format-standard","hentry","category-health","tag-university-of-gothenburg"],"acf":[],"aioseo_notices":[],"uagb_featured_image_src":{"full":false,"thumbnail":false,"medium":false,"medium_large":false,"large":false,"1536x1536":false,"2048x2048":false},"uagb_author_info":{"display_name":"The University Network","author_link":"https:\/\/www.tun.com\/home\/author\/funky_junkie\/"},"uagb_comment_info":0,"uagb_excerpt":"Research from the University of Gothenburg in Sweden sheds light on the intricacies between gut bacteria and Irritable Bowel Syndrome (IBS), potentially paving the way for innovative treatments. The study, published in the journal Cell Reports, reveals that certain gut bacteria can produce serotonin, a key substance in bowel function and mood regulation. IBS is&hellip;","_links":{"self":[{"href":"https:\/\/www.tun.com\/home\/wp-json\/wp\/v2\/posts\/30932","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.tun.com\/home\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.tun.com\/home\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.tun.com\/home\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/www.tun.com\/home\/wp-json\/wp\/v2\/comments?post=30932"}],"version-history":[{"count":9,"href":"https:\/\/www.tun.com\/home\/wp-json\/wp\/v2\/posts\/30932\/revisions"}],"predecessor-version":[{"id":30949,"href":"https:\/\/www.tun.com\/home\/wp-json\/wp\/v2\/posts\/30932\/revisions\/30949"}],"wp:attachment":[{"href":"https:\/\/www.tun.com\/home\/wp-json\/wp\/v2\/media?parent=30932"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.tun.com\/home\/wp-json\/wp\/v2\/categories?post=30932"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.tun.com\/home\/wp-json\/wp\/v2\/tags?post=30932"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}