{"id":2671,"date":"2024-07-17T12:53:05","date_gmt":"2024-07-17T12:53:05","guid":{"rendered":"https:\/\/www.tun.com\/home\/?p=2671"},"modified":"2024-10-17T17:29:06","modified_gmt":"2024-10-17T17:29:06","slug":"new-3d-atlas-of-african-clawed-frog-offers-unprecedented-insights-into-development","status":"publish","type":"post","link":"https:\/\/www.tun.com\/home\/new-3d-atlas-of-african-clawed-frog-offers-unprecedented-insights-into-development\/","title":{"rendered":"New 3D Atlas of African Clawed Frog Offers Unprecedented Insights Into Development"},"content":{"rendered":"\n<div class=\"wp-block-group\"><div class=\"wp-block-group__inner-container is-layout-constrained wp-block-group-is-layout-constrained\">\n<div class=\"wp-block-uagb-blockquote uagb-block-e7eb3fc3 uagb-blockquote__skin-border uagb-blockquote__stack-img-none\"><blockquote class=\"uagb-blockquote\"><div class=\"uagb-blockquote__content\">Researchers have created a detailed 3D anatomical atlas of the African clawed frog, revealing key developmental changes from tadpole to adult frog using cutting-edge X-ray microtomography. This data, now publicly accessible, provides invaluable insights for educators, scientists and 3D printing enthusiasts alike.<\/div><footer><div class=\"uagb-blockquote__author-wrap uagb-blockquote__author-at-left\"><\/div><\/footer><\/blockquote><\/div>\n\n\n\n<div class=\"wp-block-group is-content-justification-space-between is-nowrap is-layout-flex wp-container-core-group-is-layout-0dfbf163 wp-block-group-is-layout-flex\"><div style=\"font-size:16px;\" class=\"has-text-align-left wp-block-post-author\"><div class=\"wp-block-post-author__content\"><p class=\"wp-block-post-author__name\">The University Network<\/p><\/div><\/div>\n\n\n<div class=\"wp-block-uagb-social-share uagb-social-share__outer-wrap uagb-social-share__layout-horizontal uagb-block-ee584a31\">\n<div class=\"wp-block-uagb-social-share-child uagb-ss-repeater uagb-ss__wrapper uagb-block-ec619ce7\"><span class=\"uagb-ss__link\" data-href=\"https:\/\/www.facebook.com\/sharer.php?u=\" tabindex=\"0\" role=\"button\" aria-label=\"facebook\"><span class=\"uagb-ss__source-wrap\"><span class=\"uagb-ss__source-icon\"><svg xmlns=\"https:\/\/www.w3.org\/2000\/svg\" viewBox=\"0 0 512 512\"><path d=\"M504 256C504 119 393 8 256 8S8 119 8 256c0 123.8 90.69 226.4 209.3 245V327.7h-63V256h63v-54.64c0-62.15 37-96.48 93.67-96.48 27.14 0 55.52 4.84 55.52 4.84v61h-31.28c-30.8 0-40.41 19.12-40.41 38.73V256h68.78l-11 71.69h-57.78V501C413.3 482.4 504 379.8 504 256z\"><\/path><\/svg><\/span><\/span><\/span><\/div>\n\n\n\n<div class=\"wp-block-uagb-social-share-child uagb-ss-repeater uagb-ss__wrapper uagb-block-32d99934\"><span class=\"uagb-ss__link\" data-href=\"https:\/\/twitter.com\/share?url=\" tabindex=\"0\" role=\"button\" aria-label=\"twitter\"><span class=\"uagb-ss__source-wrap\"><span class=\"uagb-ss__source-icon\"><svg xmlns=\"https:\/\/www.w3.org\/2000\/svg\" viewBox=\"0 0 512 512\"><path d=\"M389.2 48h70.6L305.6 224.2 487 464H345L233.7 318.6 106.5 464H35.8L200.7 275.5 26.8 48H172.4L272.9 180.9 389.2 48zM364.4 421.8h39.1L151.1 88h-42L364.4 421.8z\"><\/path><\/svg><\/span><\/span><\/span><\/div>\n\n\n\n<div class=\"wp-block-uagb-social-share-child uagb-ss-repeater uagb-ss__wrapper uagb-block-1d136f14\"><span class=\"uagb-ss__link\" data-href=\"https:\/\/www.linkedin.com\/shareArticle?url=\" tabindex=\"0\" role=\"button\" aria-label=\"linkedin\"><span class=\"uagb-ss__source-wrap\"><span class=\"uagb-ss__source-icon\"><svg xmlns=\"https:\/\/www.w3.org\/2000\/svg\" viewBox=\"0 0 448 512\"><path d=\"M416 32H31.9C14.3 32 0 46.5 0 64.3v383.4C0 465.5 14.3 480 31.9 480H416c17.6 0 32-14.5 32-32.3V64.3c0-17.8-14.4-32.3-32-32.3zM135.4 416H69V202.2h66.5V416zm-33.2-243c-21.3 0-38.5-17.3-38.5-38.5S80.9 96 102.2 96c21.2 0 38.5 17.3 38.5 38.5 0 21.3-17.2 38.5-38.5 38.5zm282.1 243h-66.4V312c0-24.8-.5-56.7-34.5-56.7-34.6 0-39.9 27-39.9 54.9V416h-66.4V202.2h63.7v29.2h.9c8.9-16.8 30.6-34.5 62.9-34.5 67.2 0 79.7 44.3 79.7 101.9V416z\"><\/path><\/svg><\/span><\/span><\/span><\/div>\n<\/div>\n<\/div>\n<\/div><\/div>\n\n\n\n<p>For the first time, scientists have produced a comprehensive 3D anatomical atlas of the African clawed frog (Xenopus laevis), presenting detailed visualizations of its development from embryo to adult. This breakthrough aims to significantly enhance the understanding of various biological processes, particularly metamorphosis, in this vital model organism.<\/p>\n\n\n\n<p>Using high-resolution X-ray microtomography, the researchers meticulously documented the anatomical transformations that occur as a tadpole converts into a mature frog. This data, previously sparse and inaccessible, is now freely available, making it a groundbreaking resource for developmental biologists, educators and even 3D printing enthusiasts.<\/p>\n\n\n\n<p>\u201cThis adaptation aligns well with the frog&#8217;s life strategy, transitioning from a water-dwelling tadpole with lateral eyes to an adult with eyes positioned on top of the head for a submerged lifestyle, reminiscent of crocodilians,\u201d <a href=\"https:\/\/doi.org\/10.1093\/gigascience\/giae037\" title=\"\">noted<\/a> the study authors.<\/p>\n\n\n\n<p>The intricate changes in eye positioning during development are just one of many phenomena that can be closely observed thanks to this new atlasing.<\/p>\n\n\n\n<p>Jakub Harnos, an assistant professor in the Section of Animal Physiology and Immunology at Masaryk University and the lead author of the study, underscored the significance of this achievement. <\/p>\n\n\n\n<p>\u201cA notable gap exists in the availability of comprehensive datasets encompassing Xenopus\u2019s late developmental stages,&#8221; he said in a <a href=\"https:\/\/www.eurekalert.org\/news-releases\/1051493\" title=\"\">news release<\/a>. <\/p>\n\n\n\n<p>His team\u2019s work addresses this gap by providing detailed 3D reconstructions at various life stages, which elucidate critical anatomical changes.<\/p>\n\n\n\n<p>One fascinating aspect of the research is the drastic remodeling of the frog&#8217;s intestine during metamorphosis. Over a period of just eight days, the intestine decreases in length by approximately 75%, a transformation that highlights the dynamic nature of amphibian development. The superior imaging capability of X-ray microtomography allowed the researchers to follow this process in unprecedented detail.<\/p>\n\n\n\n<div style=\"height:20px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<figure class=\"wp-block-embed is-type-video is-provider-youtube wp-block-embed-youtube wp-embed-aspect-16-9 wp-has-aspect-ratio\"><div class=\"wp-block-embed__wrapper\">\n<iframe loading=\"lazy\" title=\"View an Anatomical Atlas of the African Clawed Frog Xenopus laevis\" width=\"500\" height=\"281\" src=\"https:\/\/www.youtube.com\/embed\/pEWu15m2z6Q?feature=oembed\" frameborder=\"0\" allow=\"accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture; web-share\" referrerpolicy=\"strict-origin-when-cross-origin\" allowfullscreen><\/iframe>\n<\/div><\/figure>\n\n\n\n<div style=\"height:11px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p>The study has also made these findings accessible to a broader audience. Forty 3D models from the atlas are available for download on platforms like Thingiverse, and interactive versions can be viewed on Sketchfab. This open science approach ensures that the data is not only accessible but also usable for various applications, from scientific research to educational purposes.<\/p>\n\n\n\n<p>The impact of this study extends beyond the realm of amphibian research. By providing detailed insights into the development and metamorphosis processes of a key vertebrate model, this 3D atlas opens new avenues for comparative studies in developmental biology and evolutionary research.<\/p>\n\n\n\n<p>Harnos emphasized the collaborative potential unlocked by this resource.<\/p>\n\n\n\n<p>\u201cOur study provides all X-ray microtomography data openly, allowing other researchers to investigate both soft and hard tissues in unprecedented detail in this key vertebrate model,\u201d he added.<\/p>\n\n\n\n<p>This comprehensive dataset, <a href=\"https:\/\/academic.oup.com\/gigascience\/article\/doi\/10.1093\/gigascience\/giae037\/7714386\" title=\"\">published<\/a> in GigaScience, marks a critical advancement in our understanding of developmental biology. It serves as a valuable tool for researchers worldwide, fostering new discoveries and applications across various scientific and educational fields.<\/p>\n\n\n\n<p><\/p>\n","protected":false},"excerpt":{"rendered":"<p>For the first time, scientists have produced a comprehensive 3D anatomical atlas of the African clawed frog (Xenopus laevis), presenting detailed visualizations of its development from embryo to adult. This breakthrough aims to significantly enhance the understanding of various biological processes, particularly metamorphosis, in this vital model organism. Using high-resolution X-ray microtomography, the researchers meticulously [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"single-no-separators","format":"standard","meta":{"_acf_changed":false,"_uag_custom_page_level_css":"","_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":""},"categories":[17],"tags":[],"class_list":["post-2671","post","type-post","status-publish","format-standard","hentry","category-tech"],"acf":[],"aioseo_notices":[],"uagb_featured_image_src":{"full":false,"thumbnail":false,"medium":false,"medium_large":false,"large":false,"1536x1536":false,"2048x2048":false},"uagb_author_info":{"display_name":"The University Network","author_link":"https:\/\/www.tun.com\/home\/author\/funky_junkie\/"},"uagb_comment_info":0,"uagb_excerpt":"For the first time, scientists have produced a comprehensive 3D anatomical atlas of the African clawed frog (Xenopus laevis), presenting detailed visualizations of its development from embryo to adult. This breakthrough aims to significantly enhance the understanding of various biological processes, particularly metamorphosis, in this vital model organism. Using high-resolution X-ray microtomography, the researchers meticulously&hellip;","_links":{"self":[{"href":"https:\/\/www.tun.com\/home\/wp-json\/wp\/v2\/posts\/2671","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.tun.com\/home\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.tun.com\/home\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.tun.com\/home\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/www.tun.com\/home\/wp-json\/wp\/v2\/comments?post=2671"}],"version-history":[{"count":9,"href":"https:\/\/www.tun.com\/home\/wp-json\/wp\/v2\/posts\/2671\/revisions"}],"predecessor-version":[{"id":2693,"href":"https:\/\/www.tun.com\/home\/wp-json\/wp\/v2\/posts\/2671\/revisions\/2693"}],"wp:attachment":[{"href":"https:\/\/www.tun.com\/home\/wp-json\/wp\/v2\/media?parent=2671"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.tun.com\/home\/wp-json\/wp\/v2\/categories?post=2671"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.tun.com\/home\/wp-json\/wp\/v2\/tags?post=2671"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}