{"id":26404,"date":"2025-06-25T16:14:32","date_gmt":"2025-06-25T16:14:32","guid":{"rendered":"https:\/\/www.tun.com\/home\/?p=26404"},"modified":"2025-06-25T16:15:31","modified_gmt":"2025-06-25T16:15:31","slug":"new-study-uncovers-how-caffeine-could-slow-cellular-aging","status":"publish","type":"post","link":"https:\/\/www.tun.com\/home\/new-study-uncovers-how-caffeine-could-slow-cellular-aging\/","title":{"rendered":"New Study Uncovers How Caffeine Could Slow Cellular Aging"},"content":{"rendered":"\n<div class=\"wp-block-group\"><div class=\"wp-block-group__inner-container is-layout-constrained wp-block-group-is-layout-constrained\">\n<div class=\"wp-block-uagb-blockquote uagb-block-e7eb3fc3 uagb-blockquote__skin-border uagb-blockquote__stack-img-none\"><blockquote class=\"uagb-blockquote\"><div class=\"uagb-blockquote__content\">A new study from Queen Mary University of London uncovers caffeine&#8217;s potential to slow cellular aging by activating the AMPK cellular fuel gauge, offering exciting possibilities for health and longevity research.<\/div><footer><div class=\"uagb-blockquote__author-wrap uagb-blockquote__author-at-left\"><\/div><\/footer><\/blockquote><\/div>\n\n\n\n<div class=\"wp-block-group is-content-justification-space-between is-nowrap is-layout-flex wp-container-core-group-is-layout-0dfbf163 wp-block-group-is-layout-flex\"><div style=\"font-size:16px;\" class=\"has-text-align-left wp-block-post-author\"><div class=\"wp-block-post-author__content\"><p class=\"wp-block-post-author__name\">The University Network<\/p><\/div><\/div>\n\n\n<div class=\"wp-block-uagb-social-share uagb-social-share__outer-wrap uagb-social-share__layout-horizontal uagb-block-ee584a31\">\n<div class=\"wp-block-uagb-social-share-child uagb-ss-repeater uagb-ss__wrapper uagb-block-ec619ce7\"><span class=\"uagb-ss__link\" data-href=\"https:\/\/www.facebook.com\/sharer.php?u=\" tabindex=\"0\" role=\"button\" aria-label=\"facebook\"><span class=\"uagb-ss__source-wrap\"><span class=\"uagb-ss__source-icon\"><svg xmlns=\"https:\/\/www.w3.org\/2000\/svg\" viewBox=\"0 0 512 512\"><path d=\"M504 256C504 119 393 8 256 8S8 119 8 256c0 123.8 90.69 226.4 209.3 245V327.7h-63V256h63v-54.64c0-62.15 37-96.48 93.67-96.48 27.14 0 55.52 4.84 55.52 4.84v61h-31.28c-30.8 0-40.41 19.12-40.41 38.73V256h68.78l-11 71.69h-57.78V501C413.3 482.4 504 379.8 504 256z\"><\/path><\/svg><\/span><\/span><\/span><\/div>\n\n\n\n<div class=\"wp-block-uagb-social-share-child uagb-ss-repeater uagb-ss__wrapper uagb-block-32d99934\"><span class=\"uagb-ss__link\" data-href=\"https:\/\/twitter.com\/share?url=\" tabindex=\"0\" role=\"button\" aria-label=\"twitter\"><span class=\"uagb-ss__source-wrap\"><span class=\"uagb-ss__source-icon\"><svg xmlns=\"https:\/\/www.w3.org\/2000\/svg\" viewBox=\"0 0 512 512\"><path d=\"M389.2 48h70.6L305.6 224.2 487 464H345L233.7 318.6 106.5 464H35.8L200.7 275.5 26.8 48H172.4L272.9 180.9 389.2 48zM364.4 421.8h39.1L151.1 88h-42L364.4 421.8z\"><\/path><\/svg><\/span><\/span><\/span><\/div>\n\n\n\n<div class=\"wp-block-uagb-social-share-child uagb-ss-repeater uagb-ss__wrapper uagb-block-1d136f14\"><span class=\"uagb-ss__link\" data-href=\"https:\/\/www.linkedin.com\/shareArticle?url=\" tabindex=\"0\" role=\"button\" aria-label=\"linkedin\"><span class=\"uagb-ss__source-wrap\"><span class=\"uagb-ss__source-icon\"><svg xmlns=\"https:\/\/www.w3.org\/2000\/svg\" viewBox=\"0 0 448 512\"><path d=\"M416 32H31.9C14.3 32 0 46.5 0 64.3v383.4C0 465.5 14.3 480 31.9 480H416c17.6 0 32-14.5 32-32.3V64.3c0-17.8-14.4-32.3-32-32.3zM135.4 416H69V202.2h66.5V416zm-33.2-243c-21.3 0-38.5-17.3-38.5-38.5S80.9 96 102.2 96c21.2 0 38.5 17.3 38.5 38.5 0 21.3-17.2 38.5-38.5 38.5zm282.1 243h-66.4V312c0-24.8-.5-56.7-34.5-56.7-34.6 0-39.9 27-39.9 54.9V416h-66.4V202.2h63.7v29.2h.9c8.9-16.8 30.6-34.5 62.9-34.5 67.2 0 79.7 44.3 79.7 101.9V416z\"><\/path><\/svg><\/span><\/span><\/span><\/div>\n<\/div>\n<\/div>\n\n\n\n<p>Scientists from the Cellular Ageing and Senescence laboratory at Queen Mary University of London\u2019s Centre for Molecular Cell Biology have made a discovery suggesting that caffeine \u2013 often consumed for its stimulating effects \u2013 could potentially help to slow down aging at the cellular level.<\/p>\n<\/div><\/div>\n\n\n\n<p>Caffeine has long been associated with health benefits, including a reduced risk of age-related diseases. However, the specifics of how caffeine interacts with cellular mechanisms and nutrient and stress-responsive gene networks have remained elusive \u2014 until now.<\/p>\n\n\n\n<p>In this pioneering research, <a href=\"https:\/\/microbialcell.com\/researcharticles\/2025a-alao-microbial-cell\/\" target=\"_blank\" rel=\"noopener\" title=\"\">published<\/a> in the journal Microbial Cell, scientists used fission yeast, a single-celled organism with surprising similarities to human cells, to delve deeper into caffeine\u2019s impact. <\/p>\n\n\n\n<p>The researchers discovered that caffeine influences aging by engaging an ancient cellular energy system.<\/p>\n\n\n\n<p>A few years ago, the same team found that caffeine prolongs cell life by acting on a growth regulator known as TOR (Target of Rapamycin). TOR is a molecular switch that regulates cell growth based on available food and energy and has been part of the evolutionary landscape for over 500 million years.<\/p>\n\n\n\n<p>However, their latest study unveiled a surprising new finding: caffeine does not directly act on the TOR switch. Instead, it activates AMPK, a cellular fuel gauge that is conserved through evolution in both yeast and humans.&nbsp;<\/p>\n\n\n\n<p>\u201cWhen your cells are low on energy, AMPK kicks in to help them cope,\u201d senior author Charalampos (Babis) Rallis, a reader in genetics, genomics and fundamental cell biology at Queen Mary University of London, said in a news release. \u201cAnd our results show that caffeine helps flip that switch.\u201d<\/p>\n\n\n\n<p>Intriguingly, AMPK is also the target of metformin, a common diabetes medication currently under scrutiny for its potential to extend human lifespan when used alongside rapamycin.<\/p>\n\n\n\n<p>By employing their yeast model, the researchers demonstrated that caffeine&#8217;s activation of AMPK affects how cells grow, repair DNA and respond to stress \u2014 processes intrinsically linked to aging and disease.<\/p>\n\n\n\n<p>\u201cThese findings help explain why caffeine might be beneficial for health and longevity,\u201d added lead author John-Patrick Alao, a postdoctoral research scientist at Queen Mary University of London. \u201cAnd they open up exciting possibilities for future research into how we might trigger these effects more directly \u2014 with diet, lifestyle, or new medicines.\u201d<\/p>\n\n\n\n<p>The next time you savor a cup of coffee, consider this: you might be doing more than just enhancing your focus. You could be giving your cells an invaluable boost.<\/p>\n\n\n\n<div style=\"height:11px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p><strong>Source:<\/strong> <a href=\"https:\/\/www.qmul.ac.uk\/media\/news\/2025\/science-and-engineering\/se\/caffeine-could-slow-cellular-ageing-new-research-shows-how.html\" target=\"_blank\" rel=\"noopener\" title=\"\">Queen Mary University of London<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Scientists from the Cellular Ageing and Senescence laboratory at Queen Mary University of London\u2019s Centre for Molecular Cell Biology have made a discovery suggesting that caffeine \u2013 often consumed for its stimulating effects \u2013 could potentially help to slow down aging at the cellular level. Caffeine has long been associated with health benefits, including a [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"single-no-separators","format":"standard","meta":{"_acf_changed":false,"_uag_custom_page_level_css":"","_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":""},"categories":[30,25],"tags":[48],"class_list":["post-26404","post","type-post","status-publish","format-standard","hentry","category-food-nutrition","category-science","tag-queen-mary-university-of-london"],"acf":[],"aioseo_notices":[],"uagb_featured_image_src":{"full":false,"thumbnail":false,"medium":false,"medium_large":false,"large":false,"1536x1536":false,"2048x2048":false},"uagb_author_info":{"display_name":"The University Network","author_link":"https:\/\/www.tun.com\/home\/author\/funky_junkie\/"},"uagb_comment_info":0,"uagb_excerpt":"Scientists from the Cellular Ageing and Senescence laboratory at Queen Mary University of London\u2019s Centre for Molecular Cell Biology have made a discovery suggesting that caffeine \u2013 often consumed for its stimulating effects \u2013 could potentially help to slow down aging at the cellular level. Caffeine has long been associated with health benefits, including a&hellip;","_links":{"self":[{"href":"https:\/\/www.tun.com\/home\/wp-json\/wp\/v2\/posts\/26404","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.tun.com\/home\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.tun.com\/home\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.tun.com\/home\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/www.tun.com\/home\/wp-json\/wp\/v2\/comments?post=26404"}],"version-history":[{"count":10,"href":"https:\/\/www.tun.com\/home\/wp-json\/wp\/v2\/posts\/26404\/revisions"}],"predecessor-version":[{"id":26436,"href":"https:\/\/www.tun.com\/home\/wp-json\/wp\/v2\/posts\/26404\/revisions\/26436"}],"wp:attachment":[{"href":"https:\/\/www.tun.com\/home\/wp-json\/wp\/v2\/media?parent=26404"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.tun.com\/home\/wp-json\/wp\/v2\/categories?post=26404"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.tun.com\/home\/wp-json\/wp\/v2\/tags?post=26404"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}