{"id":25252,"date":"2025-06-03T14:37:04","date_gmt":"2025-06-03T14:37:04","guid":{"rendered":"https:\/\/www.tun.com\/home\/?p=25252"},"modified":"2025-06-03T14:37:06","modified_gmt":"2025-06-03T14:37:06","slug":"scientists-discover-new-method-to-help-plants-fight-diseases","status":"publish","type":"post","link":"https:\/\/www.tun.com\/home\/scientists-discover-new-method-to-help-plants-fight-diseases\/","title":{"rendered":"Scientists Discover New Method to Help Plants Fight Diseases"},"content":{"rendered":"\n<div class=\"wp-block-group\"><div class=\"wp-block-group__inner-container is-layout-constrained wp-block-group-is-layout-constrained\">\n<div class=\"wp-block-uagb-blockquote uagb-block-e7eb3fc3 uagb-blockquote__skin-border uagb-blockquote__stack-img-none\"><blockquote class=\"uagb-blockquote\"><div class=\"uagb-blockquote__content\">In a study three decades in the making, researchers from Rutgers University and Brookhaven National Laboratory have uncovered new details about a plant enzyme that could transform agriculture by enhancing disease resistance in crops.<\/div><footer><div class=\"uagb-blockquote__author-wrap uagb-blockquote__author-at-left\"><\/div><\/footer><\/blockquote><\/div>\n\n\n\n<div class=\"wp-block-group is-content-justification-space-between is-nowrap is-layout-flex wp-container-core-group-is-layout-b0ffac9c wp-block-group-is-layout-flex\"><div style=\"font-size:16px\" class=\"has-text-align-left wp-block-post-author\"><div class=\"wp-block-post-author__content\"><p class=\"wp-block-post-author__name\">The University Network<\/p><\/div><\/div>\n\n\n<div class=\"wp-block-uagb-social-share uagb-social-share__outer-wrap uagb-social-share__layout-horizontal uagb-block-ee584a31\">\n<div class=\"wp-block-uagb-social-share-child uagb-ss-repeater uagb-ss__wrapper uagb-block-ec619ce7\"><span class=\"uagb-ss__link\" data-href=\"https:\/\/www.facebook.com\/sharer.php?u=\" tabindex=\"0\" role=\"button\" aria-label=\"facebook\"><span class=\"uagb-ss__source-wrap\"><span class=\"uagb-ss__source-icon\"><svg xmlns=\"https:\/\/www.w3.org\/2000\/svg\" viewBox=\"0 0 512 512\"><path d=\"M504 256C504 119 393 8 256 8S8 119 8 256c0 123.8 90.69 226.4 209.3 245V327.7h-63V256h63v-54.64c0-62.15 37-96.48 93.67-96.48 27.14 0 55.52 4.84 55.52 4.84v61h-31.28c-30.8 0-40.41 19.12-40.41 38.73V256h68.78l-11 71.69h-57.78V501C413.3 482.4 504 379.8 504 256z\"><\/path><\/svg><\/span><\/span><\/span><\/div>\n\n\n\n<div class=\"wp-block-uagb-social-share-child uagb-ss-repeater uagb-ss__wrapper uagb-block-32d99934\"><span class=\"uagb-ss__link\" data-href=\"https:\/\/twitter.com\/share?url=\" tabindex=\"0\" role=\"button\" aria-label=\"twitter\"><span class=\"uagb-ss__source-wrap\"><span class=\"uagb-ss__source-icon\"><svg xmlns=\"https:\/\/www.w3.org\/2000\/svg\" viewBox=\"0 0 512 512\"><path d=\"M389.2 48h70.6L305.6 224.2 487 464H345L233.7 318.6 106.5 464H35.8L200.7 275.5 26.8 48H172.4L272.9 180.9 389.2 48zM364.4 421.8h39.1L151.1 88h-42L364.4 421.8z\"><\/path><\/svg><\/span><\/span><\/span><\/div>\n\n\n\n<div class=\"wp-block-uagb-social-share-child uagb-ss-repeater uagb-ss__wrapper uagb-block-1d136f14\"><span class=\"uagb-ss__link\" data-href=\"https:\/\/www.linkedin.com\/shareArticle?url=\" tabindex=\"0\" role=\"button\" aria-label=\"linkedin\"><span class=\"uagb-ss__source-wrap\"><span class=\"uagb-ss__source-icon\"><svg xmlns=\"https:\/\/www.w3.org\/2000\/svg\" viewBox=\"0 0 448 512\"><path d=\"M416 32H31.9C14.3 32 0 46.5 0 64.3v383.4C0 465.5 14.3 480 31.9 480H416c17.6 0 32-14.5 32-32.3V64.3c0-17.8-14.4-32.3-32-32.3zM135.4 416H69V202.2h66.5V416zm-33.2-243c-21.3 0-38.5-17.3-38.5-38.5S80.9 96 102.2 96c21.2 0 38.5 17.3 38.5 38.5 0 21.3-17.2 38.5-38.5 38.5zm282.1 243h-66.4V312c0-24.8-.5-56.7-34.5-56.7-34.6 0-39.9 27-39.9 54.9V416h-66.4V202.2h63.7v29.2h.9c8.9-16.8 30.6-34.5 62.9-34.5 67.2 0 79.7 44.3 79.7 101.9V416z\"><\/path><\/svg><\/span><\/span><\/span><\/div>\n<\/div>\n<\/div>\n<\/div><\/div>\n\n\n\n<p class=\"wp-block-paragraph\">In a collaboration between Rutgers University and Brookhaven National Laboratory, scientists have achieved a significant breakthrough in plant biology. Through advanced crystallography and computer modeling techniques, the researchers have detailed the structure and regulatory mechanism of metacaspase 9, a pivotal plant enzyme. This discovery has the potential to revolutionize the agricultural industry by providing new ways to protect crops from devastating diseases.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The researchers, led by Eric Lam from Rutgers University-New Brunswick and Qun Liu at Brookhaven National Laboratory, have <a href=\"https:\/\/www.nature.com\/articles\/s41467-025-60253-y.epdf\" target=\"_blank\" rel=\"noopener\" title=\"\">published<\/a> their findings in the journal Nature Communications. <\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Their study elucidates how metacaspase 9, a protein enzyme known to play a crucial role in programmed cell death, can be harnessed to combat plant diseases more effectively.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u201cUnderstanding the shape and mode of activation for metacaspase 9 means we can now design long-sought tools to harness its known biological functions to protect plants from diseases and environmental stresses that could decimate crops,\u201d Liu, a structural biologist in Brookhaven&#8217;s Biology Department, said in a news release.\u00a0<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Metacaspase 9 is key to the process of programmed cell death, where cells intentionally die to benefit the organism as a whole.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">By utilizing X-ray crystallography at Brookhaven&#8217;s National Synchrotron Light Source II (NSLS-II), the team has revealed the enzyme\u2019s structure at the atomic level and observed its activation under different acidic conditions. The combination of crystallography data with molecular dynamic simulations has provided a comprehensive understanding of how the enzyme behaves and changes shape.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u201cThis work could usher in much safer and effective treatments for our crops worldwide,\u201d added Lam, a Distinguished Professor in the\u00a0Department of Plant Biology\u00a0in the Rutgers School of Environmental and Biological Sciences.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">By strengthening metacaspase 9, the researchers aim to enhance plants&#8217; natural defenses against biotrophic diseases caused by organisms like Phytophthora infestans, which was responsible for the historic potato blight in Ireland. <\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Conversely, inhibiting the enzyme&#8217;s function could prevent necrotrophic pathogens from exploiting it to kill plant cells, providing dual protection strategies.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The team has already taken steps to bring this discovery to practical application. Lam and Liu have filed a provisional patent with the U.S. Patent and Trademark Office for technologies developed from their findings. <\/p>\n\n\n\n<p class=\"wp-block-paragraph\">These innovations may lead to novel and more effective treatments for managing plant diseases, such as powdery mildew, rusts and white mold.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u201cFor many of the plant diseases, especially fungi, effective fungicide treatment options are few and, in many cases, environmental concerns are quite serious,\u201d Lam added. &#8220;By creating hyperactive versions of metacaspase 9, we may protect plants from these biotrophs by causing cell death at the invasion site earlier, thus cutting off their food supply.&#8221;<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The research team\u2019s achievements signal a monumental step forward in plant biology, offering hope for more sustainable and resilient agricultural practices worldwide. <\/p>\n\n\n\n<div style=\"height:17px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Source:<\/strong> <a href=\"https:\/\/www.rutgers.edu\/news\/scientists-find-new-way-help-plants-fight-diseases\" target=\"_blank\" rel=\"noopener\" title=\"\">Rutgers University<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>In a collaboration between Rutgers University and Brookhaven National Laboratory, scientists have achieved a significant breakthrough in plant biology. Through advanced crystallography and computer modeling techniques, the researchers have detailed the structure and regulatory mechanism of metacaspase 9, a pivotal plant enzyme. This discovery has the potential to revolutionize the agricultural industry by providing new [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"single-no-separators","format":"standard","meta":{"_acf_changed":false,"_uag_custom_page_level_css":"","_monsterinsights_skip_tracking":false,"footnotes":""},"categories":[10],"tags":[370,296],"class_list":["post-25252","post","type-post","status-publish","format-standard","hentry","category-sustainability","tag-brookhaven-national-laboratory","tag-rutgers-university"],"acf":[],"aioseo_notices":[],"aioseo_head":"\n\t\t<!-- All in One SEO 4.9.8 - aioseo.com -->\n\t<meta name=\"description\" content=\"Scientists reveal insights into plant metacaspase 9, promising new methods to protect crops from diseases that could impact agriculture worldwide.\" \/>\n\t<meta name=\"robots\" content=\"max-image-preview:large\" \/>\n\t<meta name=\"author\" content=\"The University Network\"\/>\n\t<link rel=\"canonical\" href=\"https:\/\/www.tun.com\/home\/scientists-discover-new-method-to-help-plants-fight-diseases\/\" \/>\n\t<meta name=\"generator\" content=\"All in One SEO (AIOSEO) 4.9.8\" \/>\n\t\t<meta property=\"og:locale\" content=\"en_US\" \/>\n\t\t<meta property=\"og:site_name\" content=\"TUN - 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Through advanced crystallography and computer modeling techniques, the researchers have detailed the structure and regulatory mechanism of metacaspase 9, a pivotal plant enzyme. This discovery has the potential to revolutionize the agricultural industry by providing new&hellip;","_links":{"self":[{"href":"https:\/\/www.tun.com\/home\/wp-json\/wp\/v2\/posts\/25252","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.tun.com\/home\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.tun.com\/home\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.tun.com\/home\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/www.tun.com\/home\/wp-json\/wp\/v2\/comments?post=25252"}],"version-history":[{"count":10,"href":"https:\/\/www.tun.com\/home\/wp-json\/wp\/v2\/posts\/25252\/revisions"}],"predecessor-version":[{"id":25265,"href":"https:\/\/www.tun.com\/home\/wp-json\/wp\/v2\/posts\/25252\/revisions\/25265"}],"wp:attachment":[{"href":"https:\/\/www.tun.com\/home\/wp-json\/wp\/v2\/media?parent=25252"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.tun.com\/home\/wp-json\/wp\/v2\/categories?post=25252"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.tun.com\/home\/wp-json\/wp\/v2\/tags?post=25252"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}