{"id":24226,"date":"2025-05-14T20:44:18","date_gmt":"2025-05-14T20:44:18","guid":{"rendered":"https:\/\/www.tun.com\/home\/?p=24226"},"modified":"2025-05-14T20:48:45","modified_gmt":"2025-05-14T20:48:45","slug":"new-study-reveals-health-differences-between-sexes","status":"publish","type":"post","link":"https:\/\/www.tun.com\/home\/new-study-reveals-health-differences-between-sexes\/","title":{"rendered":"New Study Reveals Health Differences Between Sexes"},"content":{"rendered":"\n<div class=\"wp-block-group\"><div class=\"wp-block-group__inner-container is-layout-constrained wp-block-group-is-layout-constrained\">\n<div class=\"wp-block-uagb-blockquote uagb-block-e7eb3fc3 uagb-blockquote__skin-border uagb-blockquote__stack-img-none\"><blockquote class=\"uagb-blockquote\"><div class=\"uagb-blockquote__content\">A new study has uncovered new insights into the biological mechanisms causing health differences between males and females, emphasizing the crucial role of non-genetic factors.<\/div><footer><div class=\"uagb-blockquote__author-wrap uagb-blockquote__author-at-left\"><\/div><\/footer><\/blockquote><\/div>\n\n\n\n<div class=\"wp-block-group is-content-justification-space-between is-nowrap is-layout-flex wp-container-core-group-is-layout-b0ffac9c wp-block-group-is-layout-flex\"><div style=\"font-size:16px\" class=\"has-text-align-left wp-block-post-author\"><div class=\"wp-block-post-author__content\"><p class=\"wp-block-post-author__name\">The University Network<\/p><\/div><\/div>\n\n\n<div class=\"wp-block-uagb-social-share uagb-social-share__outer-wrap uagb-social-share__layout-horizontal uagb-block-ee584a31\">\n<div class=\"wp-block-uagb-social-share-child uagb-ss-repeater uagb-ss__wrapper uagb-block-ec619ce7\"><span class=\"uagb-ss__link\" data-href=\"https:\/\/www.facebook.com\/sharer.php?u=\" tabindex=\"0\" role=\"button\" aria-label=\"facebook\"><span class=\"uagb-ss__source-wrap\"><span class=\"uagb-ss__source-icon\"><svg xmlns=\"https:\/\/www.w3.org\/2000\/svg\" viewBox=\"0 0 512 512\"><path d=\"M504 256C504 119 393 8 256 8S8 119 8 256c0 123.8 90.69 226.4 209.3 245V327.7h-63V256h63v-54.64c0-62.15 37-96.48 93.67-96.48 27.14 0 55.52 4.84 55.52 4.84v61h-31.28c-30.8 0-40.41 19.12-40.41 38.73V256h68.78l-11 71.69h-57.78V501C413.3 482.4 504 379.8 504 256z\"><\/path><\/svg><\/span><\/span><\/span><\/div>\n\n\n\n<div class=\"wp-block-uagb-social-share-child uagb-ss-repeater uagb-ss__wrapper uagb-block-32d99934\"><span class=\"uagb-ss__link\" data-href=\"https:\/\/twitter.com\/share?url=\" tabindex=\"0\" role=\"button\" aria-label=\"twitter\"><span class=\"uagb-ss__source-wrap\"><span class=\"uagb-ss__source-icon\"><svg xmlns=\"https:\/\/www.w3.org\/2000\/svg\" viewBox=\"0 0 512 512\"><path d=\"M389.2 48h70.6L305.6 224.2 487 464H345L233.7 318.6 106.5 464H35.8L200.7 275.5 26.8 48H172.4L272.9 180.9 389.2 48zM364.4 421.8h39.1L151.1 88h-42L364.4 421.8z\"><\/path><\/svg><\/span><\/span><\/span><\/div>\n\n\n\n<div class=\"wp-block-uagb-social-share-child uagb-ss-repeater uagb-ss__wrapper uagb-block-1d136f14\"><span class=\"uagb-ss__link\" data-href=\"https:\/\/www.linkedin.com\/shareArticle?url=\" tabindex=\"0\" role=\"button\" aria-label=\"linkedin\"><span class=\"uagb-ss__source-wrap\"><span class=\"uagb-ss__source-icon\"><svg xmlns=\"https:\/\/www.w3.org\/2000\/svg\" viewBox=\"0 0 448 512\"><path d=\"M416 32H31.9C14.3 32 0 46.5 0 64.3v383.4C0 465.5 14.3 480 31.9 480H416c17.6 0 32-14.5 32-32.3V64.3c0-17.8-14.4-32.3-32-32.3zM135.4 416H69V202.2h66.5V416zm-33.2-243c-21.3 0-38.5-17.3-38.5-38.5S80.9 96 102.2 96c21.2 0 38.5 17.3 38.5 38.5 0 21.3-17.2 38.5-38.5 38.5zm282.1 243h-66.4V312c0-24.8-.5-56.7-34.5-56.7-34.6 0-39.9 27-39.9 54.9V416h-66.4V202.2h63.7v29.2h.9c8.9-16.8 30.6-34.5 62.9-34.5 67.2 0 79.7 44.3 79.7 101.9V416z\"><\/path><\/svg><\/span><\/span><\/span><\/div>\n<\/div>\n<\/div>\n<\/div><\/div>\n\n\n\n<p class=\"wp-block-paragraph\">A recent international study led by researchers from Queen Mary University of London has uncovered crucial insights into the biological and environmental factors contributing to health differences between males and females. The findings could pave the way for more personalized health care approaches in the future.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The study, <a href=\"https:\/\/www.nature.com\/articles\/s41467-025-59034-4\" target=\"_blank\" rel=\"noopener\" title=\"\">published<\/a> in the journal Nature Communications, involved collaboration with the Berlin Institute of Health at Charit\u00e9 and the Medical Research Council (MRC) Epidemiology Unit at the University of Cambridge. <\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Utilizing data from the UK Biobank and the Fenland study, the researchers analyzed genetic links between approximately 6,000 proteins and hundreds of diseases in 56,000 men and women.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Interestingly, the researchers discovered that protein levels differed between males and females for two-thirds of the proteins analyzed. However, only about 100 of the 6,000 proteins exhibited differences in the genetic &#8220;switches&#8221; controlling their levels between the sexes.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u201cFor the first time in history, we are able to study human biology at this level of detail \u2014 across genes, proteins and more. This is the largest study to date exploring the similarities and differences in how our genetic code regulates blood protein levels between sexes,\u201d lead author Mine Koprulu, a postdoctoral researcher at Queen Mary\u2019s Precision Healthcare University Research Institute (PHURI), said in a news release.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">These findings suggest that factors beyond genetics \u2014 including lifestyle, environment, education and socioeconomic status \u2014 also play significant roles in shaping health outcomes. <\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The results highlight the necessity of considering a broad spectrum of factors when examining health disparities between sexes.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Claudia Langenberg, a director of the PHURI at Queen Mary and professor of computational medicine at the Berlin Institute of Health at Charit\u00e9, echoed this sentiment, underscoring the importance of this research for precision medicine. <\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u201cDrug development pipelines increasingly incorporate information on genetic differences in protein levels and function, and this has led to large investment in human cohorts, such as UK Biobank,\u201d she added.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Implications of this study are far-reaching, providing a potential roadmap for pharmaceutical companies and health care providers to develop more tailored treatments. By recognizing that genetic variations affecting protein regulation are generally similar across sexes, the use of such data can be more confidently applied to both male and female populations.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">However, the authors acknowledge that sex-based chromosomal categorization (XX or XY) used in their research does not always align with individuals&#8217; gender identity. This was necessary for the genetic and protein-level analyses conducted, although future studies may benefit from incorporating more comprehensive data on gender identity.<\/p>\n\n\n\n<div style=\"height:14px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Source: <\/strong><a href=\"https:\/\/www.qmul.ac.uk\/media\/news\/2025\/medicine-and-dentistry\/fmd\/new-study-sheds-light-on-health-differences-between-sexes.html\" target=\"_blank\" rel=\"noopener\" title=\"\">Queen Mary University of London<\/a><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><\/p>\n","protected":false},"excerpt":{"rendered":"<p>A recent international study led by researchers from Queen Mary University of London has uncovered crucial insights into the biological and environmental factors contributing to health differences between males and females. The findings could pave the way for more personalized health care approaches in the future. The study, published in the journal Nature Communications, involved [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"single-no-separators","format":"standard","meta":{"_acf_changed":false,"_uag_custom_page_level_css":"","_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":""},"categories":[25],"tags":[341,48,188],"class_list":["post-24226","post","type-post","status-publish","format-standard","hentry","category-science","tag-berlin-institute-of-health-at-charite","tag-queen-mary-university-of-london","tag-university-of-cambridge"],"acf":[],"aioseo_notices":[],"uagb_featured_image_src":{"full":false,"thumbnail":false,"medium":false,"medium_large":false,"large":false,"1536x1536":false,"2048x2048":false},"uagb_author_info":{"display_name":"The University Network","author_link":"https:\/\/www.tun.com\/home\/author\/funky_junkie\/"},"uagb_comment_info":0,"uagb_excerpt":"A recent international study led by researchers from Queen Mary University of London has uncovered crucial insights into the biological and environmental factors contributing to health differences between males and females. The findings could pave the way for more personalized health care approaches in the future. The study, published in the journal Nature Communications, involved&hellip;","_links":{"self":[{"href":"https:\/\/www.tun.com\/home\/wp-json\/wp\/v2\/posts\/24226","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.tun.com\/home\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.tun.com\/home\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.tun.com\/home\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/www.tun.com\/home\/wp-json\/wp\/v2\/comments?post=24226"}],"version-history":[{"count":7,"href":"https:\/\/www.tun.com\/home\/wp-json\/wp\/v2\/posts\/24226\/revisions"}],"predecessor-version":[{"id":24381,"href":"https:\/\/www.tun.com\/home\/wp-json\/wp\/v2\/posts\/24226\/revisions\/24381"}],"wp:attachment":[{"href":"https:\/\/www.tun.com\/home\/wp-json\/wp\/v2\/media?parent=24226"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.tun.com\/home\/wp-json\/wp\/v2\/categories?post=24226"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.tun.com\/home\/wp-json\/wp\/v2\/tags?post=24226"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}