{"id":14761,"date":"2025-01-13T16:58:42","date_gmt":"2025-01-13T16:58:42","guid":{"rendered":"https:\/\/www.tun.com\/home\/?p=14761"},"modified":"2025-01-13T16:58:43","modified_gmt":"2025-01-13T16:58:43","slug":"new-study-reveals-gender-bias-in-heart-disease-diagnosis","status":"publish","type":"post","link":"https:\/\/www.tun.com\/home\/new-study-reveals-gender-bias-in-heart-disease-diagnosis\/","title":{"rendered":"New Study Reveals Gender Bias in Heart Disease Diagnosis"},"content":{"rendered":"\n<div class=\"wp-block-group\"><div class=\"wp-block-group__inner-container is-layout-constrained wp-block-group-is-layout-constrained\">\n<div class=\"wp-block-uagb-blockquote uagb-block-e7eb3fc3 uagb-blockquote__skin-border uagb-blockquote__stack-img-none\"><blockquote class=\"uagb-blockquote\"><div class=\"uagb-blockquote__content\">A new UCL-led study finds that current heart disease diagnosis guidelines may miss women due to outdated thresholds. The personalized approach proposed in the study increases diagnostic accuracy, especially for women, demonstrating the potential for significant health care improvements.<\/div><footer><div class=\"uagb-blockquote__author-wrap uagb-blockquote__author-at-left\"><\/div><\/footer><\/blockquote><\/div>\n\n\n\n<div class=\"wp-block-group is-content-justification-space-between is-nowrap is-layout-flex wp-container-core-group-is-layout-b0ffac9c wp-block-group-is-layout-flex\"><div style=\"font-size:16px\" class=\"has-text-align-left wp-block-post-author\"><div class=\"wp-block-post-author__content\"><p class=\"wp-block-post-author__name\">The University Network<\/p><\/div><\/div>\n\n\n<div class=\"wp-block-uagb-social-share uagb-social-share__outer-wrap uagb-social-share__layout-horizontal uagb-block-ee584a31\">\n<div class=\"wp-block-uagb-social-share-child uagb-ss-repeater uagb-ss__wrapper uagb-block-ec619ce7\"><span class=\"uagb-ss__link\" data-href=\"https:\/\/www.facebook.com\/sharer.php?u=\" tabindex=\"0\" role=\"button\" aria-label=\"facebook\"><span class=\"uagb-ss__source-wrap\"><span class=\"uagb-ss__source-icon\"><svg xmlns=\"https:\/\/www.w3.org\/2000\/svg\" viewBox=\"0 0 512 512\"><path d=\"M504 256C504 119 393 8 256 8S8 119 8 256c0 123.8 90.69 226.4 209.3 245V327.7h-63V256h63v-54.64c0-62.15 37-96.48 93.67-96.48 27.14 0 55.52 4.84 55.52 4.84v61h-31.28c-30.8 0-40.41 19.12-40.41 38.73V256h68.78l-11 71.69h-57.78V501C413.3 482.4 504 379.8 504 256z\"><\/path><\/svg><\/span><\/span><\/span><\/div>\n\n\n\n<div class=\"wp-block-uagb-social-share-child uagb-ss-repeater uagb-ss__wrapper uagb-block-32d99934\"><span class=\"uagb-ss__link\" data-href=\"https:\/\/twitter.com\/share?url=\" tabindex=\"0\" role=\"button\" aria-label=\"twitter\"><span class=\"uagb-ss__source-wrap\"><span class=\"uagb-ss__source-icon\"><svg xmlns=\"https:\/\/www.w3.org\/2000\/svg\" viewBox=\"0 0 512 512\"><path d=\"M389.2 48h70.6L305.6 224.2 487 464H345L233.7 318.6 106.5 464H35.8L200.7 275.5 26.8 48H172.4L272.9 180.9 389.2 48zM364.4 421.8h39.1L151.1 88h-42L364.4 421.8z\"><\/path><\/svg><\/span><\/span><\/span><\/div>\n\n\n\n<div class=\"wp-block-uagb-social-share-child uagb-ss-repeater uagb-ss__wrapper uagb-block-1d136f14\"><span class=\"uagb-ss__link\" data-href=\"https:\/\/www.linkedin.com\/shareArticle?url=\" tabindex=\"0\" role=\"button\" aria-label=\"linkedin\"><span class=\"uagb-ss__source-wrap\"><span class=\"uagb-ss__source-icon\"><svg xmlns=\"https:\/\/www.w3.org\/2000\/svg\" viewBox=\"0 0 448 512\"><path d=\"M416 32H31.9C14.3 32 0 46.5 0 64.3v383.4C0 465.5 14.3 480 31.9 480H416c17.6 0 32-14.5 32-32.3V64.3c0-17.8-14.4-32.3-32-32.3zM135.4 416H69V202.2h66.5V416zm-33.2-243c-21.3 0-38.5-17.3-38.5-38.5S80.9 96 102.2 96c21.2 0 38.5 17.3 38.5 38.5 0 21.3-17.2 38.5-38.5 38.5zm282.1 243h-66.4V312c0-24.8-.5-56.7-34.5-56.7-34.6 0-39.9 27-39.9 54.9V416h-66.4V202.2h63.7v29.2h.9c8.9-16.8 30.6-34.5 62.9-34.5 67.2 0 79.7 44.3 79.7 101.9V416z\"><\/path><\/svg><\/span><\/span><\/span><\/div>\n<\/div>\n<\/div>\n<\/div><\/div>\n\n\n\n<p class=\"wp-block-paragraph\">Women may be missing diagnoses of a potentially lethal heart condition due to existing medical guidelines that fail to consider natural differences in sex and body size, according to new research led by University College London (UCL). This study, <a href=\"https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S0735109724100447\" target=\"_blank\" rel=\"noopener\" title=\"\">published<\/a> in the Journal of the American College of Cardiology, offers a new personalized approach that significantly enhances diagnostic accuracy.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The research team tested their innovative methodology on 1,600 patients with confirmed hypertrophic cardiomyopathy (HCM) and discovered that it was particularly effective for women, boosting identification rates by 20 percentage points. <\/p>\n\n\n\n<p class=\"wp-block-paragraph\">HCM is a genetic disorder characterized by the thickening of the heart&#8217;s muscular wall, which can impede blood flow and lead to severe complications such as cardiac arrest. Although approximately one in 500 people in the UK have HCM, diagnosis rates have historically skewed towards men.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u201cHaving the same cut off for everyone regardless of age, sex or size completely ignores the fact that heart wall thickness is strongly influenced by these factors,\u201d Dr. Hunain Shiwani from UCL&#8217;s Institute of Cardiovascular Science and St Bartholomew\u2019s Hospital, who led the study, said in a <a href=\"https:\/\/www.ucl.ac.uk\/news\/2025\/jan\/research-reveals-why-more-men-women-are-diagnosed-deadly-heart-disease\" target=\"_blank\" rel=\"noopener\" title=\"\">news release<\/a>.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">By tailoring diagnostic criteria to consider a person&#8217;s age, sex and body size, the researchers aim to improve early detection and reduce the incidence of misdiagnoses.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">For decades, a uniform threshold of 15 mm for left ventricle wall thickness has been the benchmark for diagnosing HCM. However, this standard was derived from studies conducted in the 1970s and fails to account for individual variability. <\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The researchers leveraged artificial intelligence to analyze 5,000 MRI heart scans, developing new, personalized thresholds for what constitutes abnormal wall thickness.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Applying these refined criteria to over 43,000 participants in the UK Biobank, the researchers observed that the personalized approach not only lowered the overall number of suspected cases but also identified a gender balance in diagnoses \u2014 44% of those flagged with potential HCM were women. This is a striking improvement, considering that under the previous uniform threshold, only one in eight diagnosed individuals was female.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The new framework not only promises to enhance accuracy in diagnosing this critical condition but also to extend its benefits across different ethnicities and clinical settings. As echocardiograms are more prevalent in routine clinical practice, the team aims to adapt the guidelines to these scans, broadening the potential for immediate application.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"> \u201cHypertrophic cardiomyopathy is a severe, potentially life-threatening condition, and missed diagnosis means people that might benefit from new and effective treatments could slip through the net,\u201d added Dr. Sonya Babu-Narayan, clinical director at the British Heart Foundation and clinical cardiologist. &#8220;By updating the traditional one-size-fits-all approach, this study redefines abnormal heart wall thickness, a key contributor to the diagnosis of hypertrophic cardiomyopathy.\u201d<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">This sophisticated approach signals a transformative shift in medical diagnostics, ensuring more equitable and precise identification of HCM, potentially saving numerous lives.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Women may be missing diagnoses of a potentially lethal heart condition due to existing medical guidelines that fail to consider natural differences in sex and body size, according to new research led by University College London (UCL). This study, published in the Journal of the American College of Cardiology, offers a new personalized approach that [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"single-no-separators","format":"standard","meta":{"_acf_changed":false,"_uag_custom_page_level_css":"","_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":""},"categories":[27],"tags":[],"class_list":["post-14761","post","type-post","status-publish","format-standard","hentry","category-health-care"],"acf":[],"aioseo_notices":[],"aioseo_head":"\n\t\t<!-- All in One SEO 4.9.8 - aioseo.com -->\n\t<meta name=\"description\" content=\"A new study reveals women may be missing diagnoses for a deadly heart condition due to outdated guidelines, proposing a personalized approach that accounts for age, sex and size to improve accuracy.\" \/>\n\t<meta name=\"robots\" content=\"max-image-preview:large\" \/>\n\t<meta name=\"author\" content=\"The University Network\"\/>\n\t<link rel=\"canonical\" href=\"https:\/\/www.tun.com\/home\/new-study-reveals-gender-bias-in-heart-disease-diagnosis\/\" \/>\n\t<meta name=\"generator\" content=\"All in One SEO (AIOSEO) 4.9.8\" \/>\n\t\t<meta property=\"og:locale\" content=\"en_US\" \/>\n\t\t<meta property=\"og:site_name\" content=\"TUN - 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