{"id":10781,"date":"2024-11-15T17:10:25","date_gmt":"2024-11-15T17:10:25","guid":{"rendered":"https:\/\/www.tun.com\/home\/?p=10781"},"modified":"2024-11-15T17:10:27","modified_gmt":"2024-11-15T17:10:27","slug":"antiseizure-meds-during-pregnancy-linked-to-neurodevelopmental-risks-in-children-study-reveals","status":"publish","type":"post","link":"https:\/\/www.tun.com\/home\/antiseizure-meds-during-pregnancy-linked-to-neurodevelopmental-risks-in-children-study-reveals\/","title":{"rendered":"Antiseizure Meds During Pregnancy Linked to Neurodevelopmental Risks in Children, Study Reveals"},"content":{"rendered":"\n<div class=\"wp-block-group\"><div class=\"wp-block-group__inner-container is-layout-constrained wp-block-group-is-layout-constrained\">\n<div class=\"wp-block-uagb-blockquote uagb-block-e7eb3fc3 uagb-blockquote__skin-border uagb-blockquote__stack-img-none\"><blockquote class=\"uagb-blockquote\"><div class=\"uagb-blockquote__content\">New research indicates that children born to mothers who took specific antiseizure medications during pregnancy face higher risks of neurodevelopmental issues. The findings encourage pregnant women on these medications to seek personalized medical advice.<\/div><footer><div class=\"uagb-blockquote__author-wrap uagb-blockquote__author-at-left\"><\/div><\/footer><\/blockquote><\/div>\n\n\n\n<div class=\"wp-block-group is-content-justification-space-between is-nowrap is-layout-flex wp-container-core-group-is-layout-b0ffac9c wp-block-group-is-layout-flex\"><div style=\"font-size:16px\" class=\"has-text-align-left wp-block-post-author\"><div class=\"wp-block-post-author__content\"><p class=\"wp-block-post-author__name\">The University Network<\/p><\/div><\/div>\n\n\n<div class=\"wp-block-uagb-social-share uagb-social-share__outer-wrap uagb-social-share__layout-horizontal uagb-block-ee584a31\">\n<div class=\"wp-block-uagb-social-share-child uagb-ss-repeater uagb-ss__wrapper uagb-block-ec619ce7\"><span class=\"uagb-ss__link\" data-href=\"https:\/\/www.facebook.com\/sharer.php?u=\" tabindex=\"0\" role=\"button\" aria-label=\"facebook\"><span class=\"uagb-ss__source-wrap\"><span class=\"uagb-ss__source-icon\"><svg xmlns=\"https:\/\/www.w3.org\/2000\/svg\" viewBox=\"0 0 512 512\"><path d=\"M504 256C504 119 393 8 256 8S8 119 8 256c0 123.8 90.69 226.4 209.3 245V327.7h-63V256h63v-54.64c0-62.15 37-96.48 93.67-96.48 27.14 0 55.52 4.84 55.52 4.84v61h-31.28c-30.8 0-40.41 19.12-40.41 38.73V256h68.78l-11 71.69h-57.78V501C413.3 482.4 504 379.8 504 256z\"><\/path><\/svg><\/span><\/span><\/span><\/div>\n\n\n\n<div class=\"wp-block-uagb-social-share-child uagb-ss-repeater uagb-ss__wrapper uagb-block-32d99934\"><span class=\"uagb-ss__link\" data-href=\"https:\/\/twitter.com\/share?url=\" tabindex=\"0\" role=\"button\" aria-label=\"twitter\"><span class=\"uagb-ss__source-wrap\"><span class=\"uagb-ss__source-icon\"><svg xmlns=\"https:\/\/www.w3.org\/2000\/svg\" viewBox=\"0 0 512 512\"><path d=\"M389.2 48h70.6L305.6 224.2 487 464H345L233.7 318.6 106.5 464H35.8L200.7 275.5 26.8 48H172.4L272.9 180.9 389.2 48zM364.4 421.8h39.1L151.1 88h-42L364.4 421.8z\"><\/path><\/svg><\/span><\/span><\/span><\/div>\n\n\n\n<div class=\"wp-block-uagb-social-share-child uagb-ss-repeater uagb-ss__wrapper uagb-block-1d136f14\"><span class=\"uagb-ss__link\" data-href=\"https:\/\/www.linkedin.com\/shareArticle?url=\" tabindex=\"0\" role=\"button\" aria-label=\"linkedin\"><span class=\"uagb-ss__source-wrap\"><span class=\"uagb-ss__source-icon\"><svg xmlns=\"https:\/\/www.w3.org\/2000\/svg\" viewBox=\"0 0 448 512\"><path d=\"M416 32H31.9C14.3 32 0 46.5 0 64.3v383.4C0 465.5 14.3 480 31.9 480H416c17.6 0 32-14.5 32-32.3V64.3c0-17.8-14.4-32.3-32-32.3zM135.4 416H69V202.2h66.5V416zm-33.2-243c-21.3 0-38.5-17.3-38.5-38.5S80.9 96 102.2 96c21.2 0 38.5 17.3 38.5 38.5 0 21.3-17.2 38.5-38.5 38.5zm282.1 243h-66.4V312c0-24.8-.5-56.7-34.5-56.7-34.6 0-39.9 27-39.9 54.9V416h-66.4V202.2h63.7v29.2h.9c8.9-16.8 30.6-34.5 62.9-34.5 67.2 0 79.7 44.3 79.7 101.9V416z\"><\/path><\/svg><\/span><\/span><\/span><\/div>\n<\/div>\n<\/div>\n<\/div><\/div>\n\n\n\n<p class=\"wp-block-paragraph\">A study conducted by a team of international researchers suggests that children born to mothers who take antiseizure medications during pregnancy may encounter increased risks of neurodevelopmental conditions.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The study analyzed data from more than 3 million children in the United Kingdom and Sweden, including 17,495 who were exposed to antiseizure medications in utero. <\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The research team discovered that children exposed to the antiseizure drug lamotrigine did not face additional risks for autism or intellectual disability compared to those exposed to other antiseizure drugs. However, other medications like valproate, topiramate and carbamazepine were linked to certain neurodevelopmental issues.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><a href=\"https:\/\/www.nature.com\/articles\/s41467-024-53813-1\" title=\"\">Published<\/a> in Nature Communications, the study underscores the importance of personalized medical consultations for pregnant women taking these medications.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u201cOur findings suggest that while certain medications may pose some risk, lamotrigine may be a less risky option,\u201d co-senior author Brian K. Lee, a professor in the Dornsife School of Public Health at Drexel University, said in a news release. \u201cActive monitoring of any antiseizure medication is critical to ensure safety and effectiveness, particularly during pregnancy.\u201d<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">In terms of absolute risk, the researchers noted that the percentage of children affected remains relatively low. Children exposed to topiramate during pregnancy were 2.5 times more likely to be diagnosed with intellectual disability, increasing their risk to 2.1% by age 12 compared to unexposed children.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">This study provides a nuanced look at the impact of these medications, diverging from earlier findings that linked topiramate or levetiracetam to ADHD.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The authors emphasized that their data does not advocate against the use of antiseizure medications but encourages patients to consult healthcare providers to determine the safest course of treatment.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u201cDecisions should be made that are tailored to individual patients,\u201d co-lead author Paul Madley-Dowd, a research fellow at the University of Bristol, said in the news release. \u201cStopping antiseizure medications can cause individual harm and harm to offspring, so these conversations always need to happen with a clinician.\u201d<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The study corroborates previous findings that have associated in utero exposure to valproate, topiramate and carbamazepine with neurodevelopmental diagnoses, such as autism, intellectual disability and ADHD. The researchers used comprehensive data from drug prescriptions in the UK and Sweden, combined with electronic health records for diagnoses.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u201cThe link between these drugs and children\u2019s neurodevelopmental outcomes is there, even if the risk isn\u2019t much higher than it is in the unexposed population,\u201d added co-lead author Viktor H. Ahlqvist, a postdoctoral researcher at Karolinska Institutet. \u201cIf you\u2019re pregnant or trying to become pregnant, and taking one of these medications, it may be worth talking with your physician to make sure you\u2019re taking the best medicine for your needs while minimizing risk to future children.\u201d<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The researchers highlight the necessity of continued investigation into the safety of these drugs across various populations as medical treatments evolve.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">This impactful Drexel University study not only shines a light on the complex relationship between antiseizure medications and neurodevelopment but also stresses the importance of personalized medical care during pregnancy. As further research unfolds, expectant mothers are encouraged to stay informed and engaged in ongoing conversations about treatment safety.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>A study conducted by a team of international researchers suggests that children born to mothers who take antiseizure medications during pregnancy may encounter increased risks of neurodevelopmental conditions. The study analyzed data from more than 3 million children in the United Kingdom and Sweden, including 17,495 who were exposed to antiseizure medications in utero. The [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"single-no-separators","format":"standard","meta":{"_acf_changed":false,"_uag_custom_page_level_css":"","_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":""},"categories":[25],"tags":[],"class_list":["post-10781","post","type-post","status-publish","format-standard","hentry","category-science"],"acf":[],"aioseo_notices":[],"uagb_featured_image_src":{"full":false,"thumbnail":false,"medium":false,"medium_large":false,"large":false,"1536x1536":false,"2048x2048":false},"uagb_author_info":{"display_name":"The University Network","author_link":"https:\/\/www.tun.com\/home\/author\/funky_junkie\/"},"uagb_comment_info":0,"uagb_excerpt":"A study conducted by a team of international researchers suggests that children born to mothers who take antiseizure medications during pregnancy may encounter increased risks of neurodevelopmental conditions. The study analyzed data from more than 3 million children in the United Kingdom and Sweden, including 17,495 who were exposed to antiseizure medications in utero. 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