{"id":22929,"date":"2017-12-28T10:15:01","date_gmt":"2017-12-28T15:15:01","guid":{"rendered":"https:\/\/www.tun.com\/blog\/?p=22929"},"modified":"2021-05-21T11:50:20","modified_gmt":"2021-05-21T15:50:20","slug":"university-calgary-brain-surgery-without-cutting-skin","status":"publish","type":"post","link":"https:\/\/www.tun.com\/blog\/university-calgary-brain-surgery-without-cutting-skin\/","title":{"rendered":"University of Calgary Researchers Perform Brain Surgery Without Cutting the Skin"},"content":{"rendered":"<p><span style=\"font-weight: 400;\">Physicians at the University of Calgary, Canada, in partnership with researchers at the Hotchkiss Brain Institute, have successfully performed nine brain surgeries on patients with essential tremor movement disorder without cutting the skin or drilling into the skull. <\/span><\/p>\n<p><span style=\"font-weight: 400;\">Using magnetic resonance guided focused ultrasound (MRgFUS) technology, the physicians are able to see the brain with real-time imaging and target a beam of high intensity ultrasound to the brain region responsible for tremor. <\/span><\/p>\n<p><span style=\"font-weight: 400;\">Focused ultrasound technology has been around for a few decades, though it has previously been unable to work through dense substances such as a skull. <\/span><\/p>\n<p><span style=\"font-weight: 400;\">In the past 10 years, new developments have been achieved to allow the technology to safely pass through bone and tissue to focus on a single point deep inside the brain, using very high power. <\/span><\/p>\n<p><span style=\"font-weight: 400;\">Physicians can now use the focused ultrasound inside an MRI to image patients and target specific areas of the brain. <\/span><\/p>\n<p><span style=\"font-weight: 400;\">\u201cWe use that ultrasound technology inside an MRI scanner to actually see where we are so that we can image the patient, who is awake, and see the structures that we\u2019re interested in targeting for the surgery and focus the ultrasound on those points deep inside the brain,\u201d said <\/span><a href=\"https:\/\/ucalgary.ca\/research\/scholars\/pike-bruce\"><span style=\"font-weight: 400;\">Dr. Bruce Pike<\/span><\/a><span style=\"font-weight: 400;\">, professor in the departments of Radiology and Clinical Neurosciences at the university\u2019s Cumming School of Medicine (CSM). <\/span><\/p>\n<p><img decoding=\"async\" class=\"aligncenter size-full wp-image-22934\" src=\"https:\/\/www.tun.com\/blog\/wp-content\/uploads\/2017\/12\/171206_mr-guided-ultrasound-002_0.jpg\" alt=\"\" width=\"400\" height=\"238\" \/><\/p>\n<p><span style=\"font-weight: 400;\">In the case of essential tremor, the most common movement disorder, the MRgFUS technology can be used to perform the same treatment as traditional, invasive surgery, but without breaking the skin. \u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">\u201cThe conventional surgery that\u2019s been done for quite a while now, called a Thalamotomy, targets a small area inside the thalamus,\u201d said Pike. \u201cThe normal approach is to drill a hole in the skull and insert a probe that passes through the healthy brain tissue all the way down to the thalamus to ultimately heat and destroy the part of the thalamus that is affected. With the focused ultrasound we\u2019re essentially doing the same procedure without having to drill a hole in the skull.\u201d <\/span><\/p>\n<p><span style=\"font-weight: 400;\">Eighty-five-year-old Elias Pharaon volunteered to undergo treatment for his essential tremor with the MRgFUS technology, and is now able to write his name successfully for the first time in five years. <\/span><\/p>\n<p><iframe title=\"Treating Essential Tremor with High Intensity Focused Ultrasound\" width=\"500\" height=\"281\" src=\"https:\/\/www.youtube.com\/embed\/br9pDazyvb4?feature=oembed\" frameborder=\"0\" allow=\"accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture; web-share\" referrerpolicy=\"strict-origin-when-cross-origin\" allowfullscreen><\/iframe><\/p>\n<p>&nbsp;<\/p>\n<p><span style=\"font-weight: 400;\">\u201cI couldn\u2019t believe the tremor in my right hand was gone,\u201d Pharaon said <\/span><a href=\"https:\/\/www.ucalgary.ca\/utoday\/issue\/2017-12-07\/revolutionary-technology-allows-brain-surgery-without-breaking-skin\"><span style=\"font-weight: 400;\">in a statement<\/span><\/a><span style=\"font-weight: 400;\">. \u201cI didn\u2019t feel anything during the procedure. I was so happy. It\u2019s changed my life. I feel like I can go out in public again.\u201d<\/span><\/p>\n<p><span style=\"font-weight: 400;\">All of the nine patients treated so far have experienced success in dramatically reducing their essential tremor. <\/span><\/p>\n<p><span style=\"font-weight: 400;\">The research team believes the MRgFUS technology can be used for more than just treating this movement disorder. <\/span><\/p>\n<p><span style=\"font-weight: 400;\">The team believes that the technology\u2019s use can be extended to treatment of <\/span><span style=\"font-weight: 400;\">Parkinson\u2019s disease, dementia, epilepsy, and brain tumours. <\/span><\/p>\n<p><span style=\"font-weight: 400;\">\u201c<\/span><span style=\"font-weight: 400;\">There are plans to extend to other conditions,\u201d Pike said. \u201cMore generally, this focused ultrasound technology has additional application beyond just functional neurosurgery. There\u2019s research going on looking at how it can be used to enhance drug delivery to brain tumors, for example.\u201d<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Two other University of Calgary physicians are involved in the research study: <\/span><a href=\"https:\/\/www.ucalgary.ca\/dcns\/about-dcns\/facultymembers\/kiss-zelma\"><span style=\"font-weight: 400;\">Dr. Zelma Kiss<\/span><\/a><span style=\"font-weight: 400;\">, neurosurgeon and professor in the departments of Clinical Neurosciences and Psychiatry at CSM; and <\/span><a href=\"https:\/\/www.ucalgary.ca\/dcns\/about-dcns\/facultymembers\/davide-martino\"><span style=\"font-weight: 400;\">Dr. Davide Martino<\/span><\/a><span style=\"font-weight: 400;\">, movement disorder specialist and associate professor in the department of Clinical Neurosciences at CSM.<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Physicians at the University of Calgary, Canada, in partnership with researchers at the Hotchkiss Brain Institute, have successfully performed nine brain surgeries on patients with essential tremor movement disorder without cutting the skin or drilling into the skull. Using magnetic resonance guided focused ultrasound (MRgFUS) technology, the physicians are able to see the brain with [&hellip;]<\/p>\n","protected":false},"author":58,"featured_media":22933,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"om_disable_all_campaigns":false,"_uag_custom_page_level_css":"","_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":""},"categories":[241,229,243],"tags":[],"class_list":["post-22929","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-medical-breakthrough","category-lead-stories","category-health"],"aioseo_notices":[],"uagb_featured_image_src":{"full":["https:\/\/www.tun.com\/blog\/wp-content\/uploads\/2017\/12\/Calgary-Brain-Surgery.png",830,533,false],"thumbnail":["https:\/\/www.tun.com\/blog\/wp-content\/uploads\/2017\/12\/Calgary-Brain-Surgery-224x144.png",224,144,true],"medium":["https:\/\/www.tun.com\/blog\/wp-content\/uploads\/2017\/12\/Calgary-Brain-Surgery-300x193.png",300,193,true],"medium_large":["https:\/\/www.tun.com\/blog\/wp-content\/uploads\/2017\/12\/Calgary-Brain-Surgery.png",830,533,false],"large":["https:\/\/www.tun.com\/blog\/wp-content\/uploads\/2017\/12\/Calgary-Brain-Surgery.png",830,533,false],"1536x1536":["https:\/\/www.tun.com\/blog\/wp-content\/uploads\/2017\/12\/Calgary-Brain-Surgery.png",830,533,false],"2048x2048":["https:\/\/www.tun.com\/blog\/wp-content\/uploads\/2017\/12\/Calgary-Brain-Surgery.png",830,533,false]},"uagb_author_info":{"display_name":"Natalie Colarossi","author_link":"https:\/\/www.tun.com\/blog\/author\/natalie-colarossi\/"},"uagb_comment_info":0,"uagb_excerpt":"Physicians at the University of Calgary, Canada, in partnership with researchers at the Hotchkiss Brain Institute, have successfully performed nine brain surgeries on patients with essential tremor movement disorder without cutting the skin or drilling into the skull. Using magnetic resonance guided focused ultrasound (MRgFUS) technology, the physicians are able to see the brain with&hellip;","featured_media_src_url":"https:\/\/www.tun.com\/blog\/wp-content\/uploads\/2017\/12\/Calgary-Brain-Surgery.png","_links":{"self":[{"href":"https:\/\/www.tun.com\/blog\/wp-json\/wp\/v2\/posts\/22929","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.tun.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.tun.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.tun.com\/blog\/wp-json\/wp\/v2\/users\/58"}],"replies":[{"embeddable":true,"href":"https:\/\/www.tun.com\/blog\/wp-json\/wp\/v2\/comments?post=22929"}],"version-history":[{"count":0,"href":"https:\/\/www.tun.com\/blog\/wp-json\/wp\/v2\/posts\/22929\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.tun.com\/blog\/wp-json\/wp\/v2\/media\/22933"}],"wp:attachment":[{"href":"https:\/\/www.tun.com\/blog\/wp-json\/wp\/v2\/media?parent=22929"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.tun.com\/blog\/wp-json\/wp\/v2\/categories?post=22929"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.tun.com\/blog\/wp-json\/wp\/v2\/tags?post=22929"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}