{"id":20524,"date":"2017-06-12T14:46:30","date_gmt":"2017-06-12T18:46:30","guid":{"rendered":"https:\/\/www.tun.com\/blog\/?p=20524"},"modified":"2019-03-12T13:10:06","modified_gmt":"2019-03-12T17:10:06","slug":"university-of-minnesota-non-invasive-device-detect-intracranial-pressure","status":"publish","type":"post","link":"https:\/\/www.tun.com\/blog\/university-of-minnesota-non-invasive-device-detect-intracranial-pressure\/","title":{"rendered":"University of Minnesota Researchers Developed First Non-Invasive Device to Detect Intracranial Pressure"},"content":{"rendered":"<p><span style=\"font-weight: 400;\">A team of researchers led by Uzma Samadani, associate professor of neurosurgery at the University of Minnesota, has developed the first non-invasive device to detect intracranial pressure, a result of brain injury. Samadani is also co-founder of Oculogica Inc., a company that was formed to commercialize the technology and make it available for use.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Concussions and other forms of traumatic brain injury (TBI) are common in the United States, and can often lead to the brain swelling and expanding within the skull. This swelling is better known as intracranial pressure (ICP). Up until Samadani\u2019s discovery, the best methods for detecting ICP were asking the patient to follow a finger with their eyes, or opening the cranium to place a pressure-detecting probe directly on the brain. <\/span><\/p>\n<p><span style=\"font-weight: 400;\">Now, Samadani and her team have developed EyeBOX<\/span><span style=\"font-weight: 400;\">CNS\u2122<\/span><span style=\"font-weight: 400;\">, a revolutionary device geared to accurately diagnose traumatic brain injury. EyeBOXCNS\u2122 <\/span><span style=\"font-weight: 400;\">detects decreased nerve function in the eye, which is a red flag for ICP. The less the nerves move within the eye, the more severe the brain swelling. <\/span><\/p>\n<p><iframe title=\"Eye-tracking: adding insight to injury\" width=\"500\" height=\"281\" src=\"https:\/\/www.youtube.com\/embed\/Pq3PPcXE4Xc?feature=oembed\" frameborder=\"0\" allow=\"accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture; web-share\" referrerpolicy=\"strict-origin-when-cross-origin\" allowfullscreen><\/iframe><\/p>\n<p><span style=\"font-weight: 400;\">In the study, EyeBOXCNS\u2122<\/span><span style=\"font-weight: 400;\">\u00a0was used to test 23 patients who needed ICP monitoring as a result from brain bleeding, tumors, or stroke. The patients watched 220 seconds of film clips while a camera recorded their eye movements. Data stemming from the study affirmed the correlation between decreased eye movement and increased ICP. <\/span><\/p>\n<p><span style=\"font-weight: 400;\">Samadani has plans to make EyeBOXCNS\u2122<\/span><span style=\"font-weight: 400;\">\u00a0a consumer device. \u201cWe have started a company to commercialize this technology and make it mainstream, affordable, and accessible to absolutely everyone,\u201d said Samadani during the TED talk shown in the video here. But, the technology is yet to go through the rigorous FDA approval system. \u201cWe hope to submit to the FDA soon. After that, commercialization will hopefully proceed expeditiously,\u201d explained Samadani to TUN. <\/span><\/p>\n<p><span style=\"font-weight: 400;\">The technology was originally geared to find \u201can outcome measure for a clinical trial to improve outcomes after brain injury,\u201d Samadani told TUN. But, \u201cthe FDA wasn&#8217;t allowing us to use MRI because the subjects had impaired consciousness and they were concerned about risks associated with an implanted device in the MRI scanner in a subject who could not relay distress.\u201d So, in an effort to follow FDA demands, the team \u201cdecided to develop an eye-tracking algorithm to assess attention. We serendipitously found that brain-injured subjects were not capable of coordinated eye movement in the same way as normals.\u201d<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Concussions and traumatic brain injuries are severe medical issues with very few methods of detection or rehabilitation. <\/span><a href=\"http:\/\/www.headcasecompany.com\/concussion_info\/stats_on_concussions_sports\"><span style=\"font-weight: 400;\">Four to five million Americans<\/span><\/a><span style=\"font-weight: 400;\"> suffer from a concussion every year, and 5.3 million are estimated to live with a TBI-related disability. But now, \u201cconcussion does not have to be invisible,\u201d Samadani said during her TED talk. <\/span><\/p>\n<p><span style=\"font-weight: 400;\">\u201cWhen something is invisible you can\u2019t run clinical trials, you can\u2019t test whether something prevents it, you can\u2019t test whether something treats it,\u201d said Samadani during her TED talk. But, when something is not invisible, imagine what you can do. You can improve quality of life and you can save lives.\u201d<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Middle and high school students make up a large percentage of concussion patients. One in five high school athletes will experience a concussion, and the more concussions you have the higher the likelihood of getting another. Thirty-three percent of high school athletes suffer from a concussion experience two or more times in the same year. <\/span><\/p>\n<p><span style=\"font-weight: 400;\">Oculogica set up testing at the children&#8217;s hospital of Philadelphia Concussion Center and \u201csaw, sadly enough, that concussion in children results in just as severe eye movement abnormalities as it does in adults,\u201d said Samadani during her TED talk. EyeBOXCNS\u2122<\/span><span style=\"font-weight: 400;\">\u00a0can effectively test the severity of a concussion to limit potential pressure build up in the brain. This is especially crucial for a young and developing brain. <\/span><\/p>\n<p><span style=\"font-weight: 400;\">Samadani is very optimistic about the potential of her technology. \u201cEye tracking will do for brain injury what EEG did for seizures &#8211; enable better classification,\u201d said Samadani. EyeBOXCNS\u2122<\/span><span style=\"font-weight: 400;\">\u00a0will revolutionize ICP treatment and open doors for further advanced research and development. <\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>A team of researchers led by Uzma Samadani, associate professor of neurosurgery at the University of Minnesota, has developed the first non-invasive device to detect intracranial pressure, a result of brain injury. Samadani is also co-founder of Oculogica Inc., a company that was formed to commercialize the technology and make it available for use. Concussions [&hellip;]<\/p>\n","protected":false},"author":32,"featured_media":20527,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"om_disable_all_campaigns":false,"_uag_custom_page_level_css":"","_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":""},"categories":[231,232,241,230,229,523,524,525,526,527,243],"tags":[],"class_list":["post-20524","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-campus-news","category-technology","category-medical-breakthrough","category-news","category-lead-stories","category-university-of-minnesota-crookston","category-university-of-minnesota-duluth","category-university-of-minnesota-morris","category-university-of-minnesota-rochester","category-university-of-minnesota-twin-cities","category-health"],"aioseo_notices":[],"uagb_featured_image_src":{"full":["https:\/\/www.tun.com\/blog\/wp-content\/uploads\/2017\/06\/University-of-Minnesota-EyeBOXCNS.jpg",830,533,false],"thumbnail":["https:\/\/www.tun.com\/blog\/wp-content\/uploads\/2017\/06\/University-of-Minnesota-EyeBOXCNS-224x144.jpg",224,144,true],"medium":["https:\/\/www.tun.com\/blog\/wp-content\/uploads\/2017\/06\/University-of-Minnesota-EyeBOXCNS-300x193.jpg",300,193,true],"medium_large":["https:\/\/www.tun.com\/blog\/wp-content\/uploads\/2017\/06\/University-of-Minnesota-EyeBOXCNS.jpg",830,533,false],"large":["https:\/\/www.tun.com\/blog\/wp-content\/uploads\/2017\/06\/University-of-Minnesota-EyeBOXCNS.jpg",830,533,false],"1536x1536":["https:\/\/www.tun.com\/blog\/wp-content\/uploads\/2017\/06\/University-of-Minnesota-EyeBOXCNS.jpg",830,533,false],"2048x2048":["https:\/\/www.tun.com\/blog\/wp-content\/uploads\/2017\/06\/University-of-Minnesota-EyeBOXCNS.jpg",830,533,false]},"uagb_author_info":{"display_name":"Jackson Schroeder","author_link":"https:\/\/www.tun.com\/blog\/author\/jackson-schroeder\/"},"uagb_comment_info":0,"uagb_excerpt":"A team of researchers led by Uzma Samadani, associate professor of neurosurgery at the University of Minnesota, has developed the first non-invasive device to detect intracranial pressure, a result of brain injury. Samadani is also co-founder of Oculogica Inc., a company that was formed to commercialize the technology and make it available for use. Concussions&hellip;","featured_media_src_url":"https:\/\/www.tun.com\/blog\/wp-content\/uploads\/2017\/06\/University-of-Minnesota-EyeBOXCNS.jpg","_links":{"self":[{"href":"https:\/\/www.tun.com\/blog\/wp-json\/wp\/v2\/posts\/20524","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.tun.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.tun.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.tun.com\/blog\/wp-json\/wp\/v2\/users\/32"}],"replies":[{"embeddable":true,"href":"https:\/\/www.tun.com\/blog\/wp-json\/wp\/v2\/comments?post=20524"}],"version-history":[{"count":0,"href":"https:\/\/www.tun.com\/blog\/wp-json\/wp\/v2\/posts\/20524\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.tun.com\/blog\/wp-json\/wp\/v2\/media\/20527"}],"wp:attachment":[{"href":"https:\/\/www.tun.com\/blog\/wp-json\/wp\/v2\/media?parent=20524"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.tun.com\/blog\/wp-json\/wp\/v2\/categories?post=20524"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.tun.com\/blog\/wp-json\/wp\/v2\/tags?post=20524"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}